FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4VT057244
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General Information
Symbol
Scer\GAL4VT057244
Species
S. cerevisiae
Name
FlyBase ID
FBal0313047
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{VT057244-GAL4}
Also Known As
VT57244-GAL4, VT57244
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Meadows, 2015.3.13)
Progenitor genotype
Carried in construct
P{VT057244-GAL4}
Cytology
Description

A 2295 base pair fragment from the flanking non-coding or intronic region of SK is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

(Meadows, 2015.3.13)
Allele components
Component
Use(s)
Regulatory region(s)
VT057244
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      mushroom body output neuron 1
      (Shyu et al., 2017)
      adult brain | restricted
      (Shyu et al., 2017)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Blockade of all &agr';β' Kenyon cells (by expressing the temperature sensitive shits.UAS.cUa under the control of Scer\GAL4VT057244 and shifted to the permissive 33[o]C) decreases olfactory medium term memory (1h) when experiment is carried out in crowded conditions (groups of 32 flies - socially facilitated memory).

      (Muria et al., 2021)

      Inhibition (using shits1.IVS.p10.20xUAS at 32[o]C) of Scer\GAL4VT057244 cells in adults during consolidation alone, or acquisition and consolidation, but not acquisition or retrieval alone, significantly reduces 24-hour associative olfactory water-reward memory, compared to controls; inhibition has no effect on water preference, compared to controls.

      (Shyu et al., 2017)

      Inhibition (using shi1.UAS at 31[o]C) of Scer\GAL4VT057244 cells in adults during testing only significantly reduces 3-hour aversive olfactory anaesthesia-resistant memory, compared to controls, with no effect on odor or shock avoidance.

      (Yang et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4VT057244
      Name Synonyms
      Secondary FlyBase IDs
        References (13)