Gorab¹ homozygotes emerging at 25[o]C move slowly and are uncoordinated, and when raised at 29[o]C are unable to climb or fly. The femoral chordotonal organs display highly disorganized ciliary rootlets which are often disconnected from basal bodies, display reduced or absent proximal basal bodies and display radial symmetry defects in the remaining mother centriole-derived basal body, as compared to controls; the defective symmetry extends from the basal body through the transition zone to the distal part of the cilium. Mitotic spindles in Gorab¹ homozygous larval wing disc cells show centrosome loss, as compared to controls.

Embryos derived from mothers simultaneously homozygous for Gorab¹ and expressing Gorab^WT.Ubq.N-GFP under the control of Scer\GAL4^elav-C155 show a severe decrease in the number of mitotic cell cycles, associated with mitotic spindle defects (i.e. centrosome loss and multipolar spindles), as compared to controls.