FlyBase Allele Report: Scer\GAL4[VP16.PDZ-GEF]

General Information

Symbol

Scer\GAL4^VP16.PDZ-GEF

Species

S. cerevisiae

Name

FlyBase ID

FBal0345059

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{PDZ-GEF-GAL4::VP16}

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Boettner and Van Aelst, 2007)

Progenitor genotype

Carried in construct

P{PDZ-GEF-GAL4::VP16}

Cytology

Description

A PDZ-GEF promoter fragment staring 2975bp upstream of the translation start codon drives expression of GAL4::VP16.

(Boettner and Van Aelst, 2007)

Allele components

Component

Use(s)

Regulatory region(s)

PDZ-GEF

Encoded product / tool

GAL4::VP16

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter or direct label

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 15

ectoderm

(Boettner and Van Aelst, 2007)

Additional Information

Statement

Reference

Marker for

Reflects expression of

PDZ-GEF

(Boettner and Van Aelst, 2007)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell migration | embryonic stage, with Rap1^{N17.UAS.Tag:MYC}

(Boettner and Van Aelst, 2007)

abnormal cell migration | embryonic stage, with Rap1^{V12.UAS.Tag:MYC}

(Boettner and Van Aelst, 2007)

lethal - all die during embryonic stage, with Rap1^{N17.UAS.Tag:MYC}

(Boettner and Van Aelst, 2007)

lethal - all die during embryonic stage, with Rap1^{V12.UAS.Tag:MYC}

(Boettner and Van Aelst, 2007)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has abnormal cell migration | embryonic stage phenotype, non-enhanceable by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has abnormal cell migration | embryonic stage phenotype, non-enhanceable by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

NOT suppressed by

Statement

Reference

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has lethal - all die during embryonic stage phenotype, non-suppressible by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has lethal - all die during embryonic stage phenotype, non-suppressible by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has abnormal cell migration | embryonic stage phenotype, non-suppressible by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has abnormal cell migration | embryonic stage phenotype, non-suppressible by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

NOT Enhancer of

Statement

Reference

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of abnormal cell migration | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-enhancer of abnormal cell migration | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of abnormal cell migration | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of abnormal cell migration | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Suppressor of

Statement

Reference

Scer\GAL4^VP16.PDZ-GEF/Rap1^UAS.Tag:MYC is a suppressor of increased mortality during development phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of increased mortality during development phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/Rap1^UAS.Tag:MYC is a suppressor of abnormal cell migration | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of abnormal cell migration | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

NOT Suppressor of

Statement

Reference

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of lethal - all die during embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of lethal - all die during embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of abnormal cell migration | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of abnormal cell migration | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-suppressor of lethal - all die during embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of lethal - all die during embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-suppressor of abnormal cell migration | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of abnormal cell migration | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryo phenotype, non-enhanceable by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryo phenotype, non-enhanceable by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryonic/first instar larval cuticle | embryonic stage phenotype, non-enhanceable by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryonic/first instar larval cuticle | embryonic stage phenotype, non-enhanceable by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has ectoderm | embryonic stage phenotype, non-enhanceable by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has ectoderm | embryonic stage phenotype, non-enhanceable by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

NOT suppressed by

Statement

Reference

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryo phenotype, non-suppressible by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has ectoderm | embryonic stage phenotype, non-suppressible by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryonic/first instar larval cuticle | embryonic stage phenotype, non-suppressible by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has ectoderm | embryonic stage phenotype, non-suppressible by PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryo phenotype, non-suppressible by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF has embryonic/first instar larval cuticle | embryonic stage phenotype, non-suppressible by PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

NOT Enhancer of

Statement

Reference

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryo phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryo phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryonic/first instar larval cuticle | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of ectoderm | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryonic/first instar larval cuticle | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-enhancer of embryo phenotype of cno²

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-enhancer of embryonic/first instar larval cuticle | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-enhancer of ectoderm | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryo phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of embryonic/first instar larval cuticle | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of ectoderm | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-enhancer of ectoderm | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Suppressor of

Statement

Reference

Scer\GAL4^VP16.PDZ-GEF/Rap1^UAS.Tag:MYC is a suppressor of embryo phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/Rap1^UAS.Tag:MYC is a suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/Rap1^UAS.Tag:MYC is a suppressor of ectoderm | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of embryo phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of ectoderm | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

NOT Suppressor of

Statement

Reference

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryo phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of ectoderm | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-suppressor of embryo phenotype of cno²

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa is a non-suppressor of ectoderm | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryo phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}/Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of ectoderm | embryonic stage phenotype of cno²

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^UAS.cBa, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of ectoderm | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryo phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

PDZ-GEF^{UAS.Tag:Myr(Src42A)}, Scer\GAL4^VP16.PDZ-GEF is a non-suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^VP16.PDZ-GEF

(Boettner and Van Aelst, 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^VP16.PDZ-GEF/PDZ-GEF^UAS.cBa partially rescues PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^VP16.PDZ-GEF

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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