FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Kdm5I1
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General Information
Symbol
Dmel\Kdm5I1
Species
D. melanogaster
Name
FlyBase ID
FBal0408793
Feature type
allele
Associated gene
Dmel\Kdm5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Herz and Bergmann, 2024)
Mutagen
ethyl methanesulfonate
(Herz and Bergmann, 2024)
Progenitor genotype
Cytology
Description

Amino acid replacement: ?45term.

(Herz and Bergmann, 2024)

Premature STOP codon at codon 45 in Kdm5.

(Herz and Bergmann, 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:5,996,358..5,996,358 [-]
Nucleotide change:

C5996358T

Amino acid change:

R45term | Kdm5-PA; R45term | Kdm5-PB; R45term | Kdm5-PC; R45term | Kdm5-PD; R45term | Kdm5-PE; R45term | Kdm5-PF

Reported amino acid change:

?45term

Comment:

Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Herz and Bergmann, 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by Rbf14/Rbf[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by Rbf14/Rbf[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by Scer\GAL4Act.PU/Kdm5UASp.cSa

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by Rbf[+]/Rbf16803

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by Rbf[+]/Rbf16803

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by Mycdm-1/Myc[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by Mycdm-1/Myc[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by Scer\GAL4Act.PU/Kdm5UASp.cSa

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by MycBG00605/Myc[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by MycBG00605/Myc[+]

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has visible | adult stage | somatic clone - tissue specific phenotype, enhanceable by Scer\GAL4Act.PU/Kdm5JmjC.mut.UASp

      (Herz and Bergmann, 2024)

      Kdm5I1, hidGMR.PG has decreased size | adult stage | somatic clone - tissue specific phenotype, enhanceable by Scer\GAL4Act.PU/Kdm5JmjC.mut.UASp

      (Herz and Bergmann, 2024)
      Suppressed by
      Enhancer of
      Statement
      Reference

      Kdm5[+]/Kdm5I1 is an enhancer of visible | adult stage | dominant phenotype of rlSem

      (Herz and Bergmann, 2024)
      Suppressor of
      NOT Suppressor of
      Other
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Statement
      Reference

      Kdm5I1, hidGMR.PG has eye | somatic clone - tissue specific phenotype, suppressible by E2f1[+]/E2f1i2

      (Herz and Bergmann, 2024)
      Enhancer of
      Statement
      Reference

      Kdm5[+]/Kdm5I1 is an enhancer of wing vein phenotype of rlSem

      (Herz and Bergmann, 2024)
      Suppressor of
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Kdm5I1
      (Herz and Bergmann, 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)