Please see the JBrowse view of Dmel\Ptpa for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Associates with PP2A heterodimeric core enzyme PP2A(D), composed of a catalytic subunit (subunit C) and a constant regulatory subunit (PR65 or subunit A) (By similarity). Interacts with the catalytic subunit Pp4-19C of the serine/threonine-protein phosphatase 4 (PP4) complex; thereby mediating basal localization of the Miranda (Mira) complex; probably by facilitating the dephosphorylation of Mira (PubMed:26586222).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ptpa using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Ptpa is expressed in many cells in third instar larva including all the neuroblasts in the brain.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Ptpa in JBrowse2-10
2-7.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
