mei-910, DS02740.10, BG:DS02740.10
Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\c(2)M using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\c(2)M in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
c(2)M appears to function within the synaptonemal complex during meiotic prophase I but possibly not thereafter, suggesting that it may not confer sister chromatic cohesion needed for meiosis I and II chromosome segregation.
Mutants exhibit high levels of nondisjunction. The number of crossovers seen is reduced to less than 10%.
Identification: genetic screen for meiotic mutants.
A meiotic precondition genes, required for a step prior to the actual recombination event that produces a crossover.
Mutants show defective meiosis.