Gene model reviewed during 5.46
Antisense UTR: 5' UTR is antisense to Trxr-1 on opposite strand.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sni using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\sni in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The function of sni is required to prevent neuronal apoptosis induced by oxidative stress.
Mutants show brain degeneration. The phenotype is especially evident in the cortex of the first optic ganglion, the lamina, where neurons die in an age-dependent manner followed by apoptosis of glial cells. Mutant flies also show a locomotor phenotype and reduced life span.