FlyBase Gene Report: Dmel\sni

General Information

Symbol

Dmel\sni

Species

D. melanogaster

Name

sniffer

Annotation Symbol

CG10964

Feature Type

protein_coding_gene

FlyBase ID

FBgn0030026

Gene Model Status

Current

Stock Availability

7 publicly available

Enzyme Name (EC)

carbonyl reductase (NADPH) (1.1.1.184)

Gene Summary

sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

7D22-7D22

Sequence location

X:8,241,501..8,244,016 [-]

Recombination map

1-22

RefSeq locus

NC_004354 REGION:8241501..8244016

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables carbonyl reductase (NADPH) activity

inferred from direct assay

(Martin et al., 2011, Botella et al., 2004)

enables cardiolipin dehydrogenase (NAD+) activity

inferred from direct assay

(Boynton and Shimkets, 2015)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables carbonyl reductase (NADPH) activity

inferred from biological aspect of ancestor with PANTHER:PTN001214646

(GO Reference Genome Project, 2011-)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in mitochondrial matrix

inferred from direct assay

(Chen et al., 2015)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN002882605

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

CARBONYL REDUCTASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

carbonyl reductase (NADPH) activity

a secondary alcohol + NADP(+) = a ketone + NADPH + H(+) (1.1.1.184)

RHEA 19257: cardiolipin dehydrogenase (NAD+) activity
RHEA 81091:

Summaries

Gene Snapshot

Gene Group (FlyBase)

CARBONYL REDUCTASES -: Carbonyl reductases belong to the family of short chain dehydrogenases/reductases (SDR). They are NADPH-dependent, cytosolic enzymes with broad substrate specificity for many endogenous and xenobiotic carbonyl compounds, catalyzing the reduction of aldehydes and ketones into secondary alcohols. (Adapted from PMID:11154733.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\sni for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9W3H4)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

PDB - An information portal to biological macromolecular structures

1SNY

Comments on Gene Model

Gene model reviewed during 5.46

Antisense UTR: 5' UTR is antisense to Trxr-1 on opposite strand.

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

sni-RA

FBtr0071183

NM_132238

1105

247

sni-RB

FBtr0344985

NM_001298083

1761

247

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

sni-PA

FBpp0071131

26.5

247

8.90

FBpp0311239

26.5

247

8.90

Q9W3H4

NP_001285012

AHN59483

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

247 aa isoforms: sni-PA, sni-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

PDB - An information portal to biological macromolecular structures

1SNY

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9W3H4

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sni using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

sni_1
sni_2

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.18

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in mitochondrial matrix

inferred from direct assay

(Chen et al., 2015)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\sni in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\sni

View exonic expression by tissue for Dmel\sni

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0030026

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31761/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0030026

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0030026

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0030026

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10964

Flygut - An atlas of the Drosophila adult midgut

FBgn0030026

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 9 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of sni

Transgenic constructs containing regulatory region of sni

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene partially disrupted in

Df(1)sni²

(Botella et al., 2004)

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

sni¹

viable, with Scer\GAL4^Mef2.PR

sni^GD7147

viable, with Scer\GAL4^pnr-MD237

sni^GD7147

viable, with Scer\GAL4^tin.CΔ4

sni^GD7147

Other Phenotypes

Allele

abnormal circadian rhythm

sni¹

abnormal flight, with Scer\GAL4^Mef2.PR

sni^GD7147

abnormal locomotor behavior | adult stage

sni¹

abnormal neuroanatomy

sni¹

abnormal neuroanatomy | adult stage | progressive

sni¹

abnormal neuroanatomy | progressive

sni^unspecified

abnormal neurophysiology | adult stage

sni¹

abnormal sleep | adult stage

sni¹

chemical resistant, with Scer\GAL4^Act5C.PI

sni^UAS.cBa

chemical sensitive

sni¹

decreased speed of aging | conditional, with Scer\GAL4^Act5C.PI

sni^UAS.cBa

increased cell death

sni¹

increased rate of adult locomotory behavior | adult stage

sni¹

increased sleep | adult stage

sni¹

increased speed of aging

sni¹

short lived, with Scer\GAL4^Act5C.PI

sni^UAS.cBa

short lived | conditional

sni¹

Phenotype manifest in

Allele

adult brain | progressive

sni¹

adult dorsal fan-shaped body

sni¹

dopaminergic neuron | progressive

sni^unspecified

lamina & glial cell

sni¹

lamina monopolar neuron

sni¹

vacuole | adult stage | progressive

sni¹

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (31)

Hsap\CBR3

4 of 14

Yes

Hsap\CBR1

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (29)

Rnor\Cbr3

4 of 14

Yes

Rnor\Cbr1

3 of 14

Yes

Rnor\LOC102556347

3 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Sdr9c7

1 of 14

Rnor\Sdr16c5

1 of 14

Rnor\Sdr16c6

1 of 14

Mus musculus (laboratory mouse) (35)

Mmus\Cbr1

3 of 14

Yes

Mmus\Cbr3

3 of 14

Yes

Mmus\Gm5678

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (26)

Xtro\MGC147117

9 of 13

Yes

Xtro\ptp4a3

9 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

Yes

Xtro\cbr1.2

1 of 13

Yes

Xtro\cbr1.3

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (47)

Drer\si:dkey-12e7.4

13 of 14

Yes

Drer\zgc:110339

13 of 14

Yes

Drer\zgc:158868

9 of 14

Yes

Drer\zgc:92161

8 of 14

Yes

Drer\si:ch73-186j5.2

7 of 14

Yes

Drer\zgc:112146

7 of 14

Yes

Drer\zgc:123284

7 of 14

Yes

Drer\zgc:163083

7 of 14

Yes

Drer\zgc:65997

6 of 14

Yes

Drer\cbr1

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:ch211-107o10.3

1 of 14

Drer\si:dkey-73n8.3

1 of 14

Drer\si:dkey-94e7.2

1 of 14

Drer\si:dkey-174n20.1

1 of 14

Drer\si:dkey-221h15.4

1 of 14

Drer\zgc:64106

1 of 14

Drer\zgc:101858

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (44)

Cele\C55A6.3

14 of 14

Yes

Cele\C55A6.4

14 of 14

Yes

Cele\C55A6.6

14 of 14

Yes

Cele\C55A6.7

14 of 14

Yes

Cele\sdz-8

14 of 14

Yes

Cele\C30G12.2

13 of 14

Yes

Cele\F20G2.1

13 of 14

Yes

Cele\F20G2.2

13 of 14

Yes

Cele\ZK697.14

13 of 14

Yes

Cele\dhs-12

11 of 14

Yes

Cele\dhs-31

8 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (23)

Agam\AgaP_AGAP000564

12 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (48)

Atha\AT4G20760

10 of 13

Yes

Atha\AT3G59710

3 of 13

Yes

Atha\AT5G51030

3 of 13

Yes

Atha\AT5G61830

3 of 13

Yes

Atha\SDR1

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (8)

Scer\OSI1

12 of 13

Yes

Scer\AYR1

2 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (11)

Spom\SPCC24B10.20

12 of 12

Yes

Spom\SPCC663.06c

12 of 12

Yes

Spom\SPCC663.08c

12 of 12

Yes

Spom\SPCC663.09c

12 of 12

Yes

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (4)

Ecol\fabG

1 of 11

Yes

Ecol\ucpA

1 of 11

Yes

Ecol\ybbO

1 of 11

Yes

Ecol\ygfF

1 of 11

Yes

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:sni. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (30)

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Pdh

1 of 13

Ppdh

1 of 13

Rdh1

1 of 13

sro

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Allele

Disease

Evidence

References

sni¹

model of neurodegenerative disease

CEA

(Krishnan et al., 2012)

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

sni¹

model of neurodegenerative disease

is exacerbated by per⁰¹

(Krishnan et al., 2012)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CBR3; carbonyl reductase 3

4 of 14

603608

CBR1; carbonyl reductase 1

3 of 14

114830

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

sni

suppressible

(Rorsman et al., 2025)

sni

enhanceable

per

(Krishnan et al., 2012)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

58222

DroID - A comprehensive database of gene and protein interactions.

FBgn0030026

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-22

Cytogenetic map

7D22-7D22

Sequence location

X:8,241,501..8,244,016 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

7D22-7D22

Limits computationally determined from genome sequence between P{EP}sdt^EP1143 and P{EP}CG1632^EP1583

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-22

(FlyBase, 2016)

1-22.6

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

31978

y¹ v¹; P{TRiP.JF03412}attP2

22439

y¹ w^67c23 P{EPgy2}Trxr1^EY20992 sni^EY20992

86438

y¹ w^* TI{CRIMIC.TG4.0}sni^{CR01541-TG4.0} Trxr1^{CR01541-TG4.0-X}/FM7h

10779

10964R-3

v106219

v27342

w¹¹¹⁸; P{GD7147}v27342/TM3

Genomic Clones (10)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (15)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD36273

Other clones

DPiM_LD36273

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0030026

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0030026

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

sni prevents oxidative stress-induced neurodegeneration.

(Botella et al., 2004)

The function of sni is required to prevent neuronal apoptosis induced by oxidative stress.

(Botella et al., 2001)

Mutants show brain degeneration. The phenotype is especially evident in the cortex of the first optic ganglion, the lamina, where neurons die in an age-dependent manner followed by apoptosis of glial cells. Mutant flies also show a locomotor phenotype and reduced life span.

(Botella et al., 2001)

Relationship to Other Genes

Source for database merge of

Source for merge of: sni anon-WO03040301.183

(FlyBase, 1996-)

Additional comments

Source for merge of sni anon-WO03040301.183 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: sni CG10964

(Botella, 2002.3.6)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG10964

(Chen et al., 2015, Qurashi et al., 2012, Cammarato et al., 2011, Keleman et al., 2009.8.5, Perkins et al., 2009)

SNI

(Rival et al., 2009)

Sni

(Rahman et al., 2017, Qurashi et al., 2012)

anon-WO03040301.183

sni

(Hu et al., 2024, Cabey et al., 2022, Gene Disruption Project members, 2018-, Giebultowicz and Long, 2015, Japanese National Institute of Genetics, 2012.5.21, Krishnan et al., 2012, Gruenewald et al., 2009, Botella et al., 2008)

Name Synonyms

Sniffer

(Boynton and Shimkets, 2015, Qurashi et al., 2012, Rival et al., 2009, Botella et al., 2003)

sniffer

(Cabey et al., 2022, Krishnan et al., 2012, Cammarato et al., 2011, Martin et al., 2011, Botella et al., 2008, Sgraja et al., 2004, Botella et al., 2001)

Secondary FlyBase IDs

FBgn0066834

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 38 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

31761

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9W3H4

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9W3H4

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9W3H4

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0030026

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31761/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0030026

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0030026

FlyMine - An integrated database for Drosophila genomics

FBgn0030026

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG10964

MARRVEL_MODEL - MARRVEL (model organism gene)

31761

PDB - An information portal to biological macromolecular structures

1SNY

Linkouts

BioGRID - A database of protein and genetic interactions.

58222

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0030026

DroID - A comprehensive database of gene and protein interactions.

FBgn0030026

DRSC - Results frm RNAi screens

FBgn0030026

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

sni_1
sni_2

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0030026

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0030026

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10964

Flygut - An atlas of the Drosophila adult midgut

FBgn0030026

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC032498

References (51)

The following external sites may use different assemblies or annotations than FlyBase.

1.18

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