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Citation
Deutsch, J., Laval, M., Lepesant, J.A., Maschat, F., Pourrain, F., Rat, L. (1989). Larval fat body-specific gene expression in Drosophila melanogaster.  Dev. Genet. 10(3): 220--231.
FlyBase ID
FBrf0049520
Publication Type
Research paper
Abstract

The Pl gene, together with the LSP-1 alpha, -1 beta, and -1 gamma, LSP-2, and P6 genes, is expressed exclusively in the larval fat body of D. melanogaster during the third instar. In vivo mapping of the cis-acting regulatory sequences of the P1 gene was carried out using hybrid constructs with three different reporter genes and a combination of transient and germline transformation assays. This revealed that regulatory elements involved in the setting up of the temporal and spatial specificities of transcription of the P1 gene are located in a short DNA region immediately upstream of the mRNA transcription start. This region includes an element that behaves as a fat-body transcriptional enhancer and element(s) required for ecdysone inducibility of transcription of the P1 gene.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Genet.
    Title
    Developmental Genetics
    Publication Year
    1979-1999
    ISBN/ISSN
    0192-253X
    Data From Reference
    Alleles (6)
    Genes (10)
    Experimental Tools (1)
    Transgenic Constructs (2)