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Citation
Mello, J.A., Almouzni, G. (2001). The ins and outs of nucleosome assembly.  Curr. Opin. Genet. Dev. 11(2): 136--141.
FlyBase ID
FBrf0136684
Publication Type
Review
Abstract

De novo nucleosome assembly coupled to DNA replication and repair in vitro involves the histone chaperone chromatin assembly factor 1 (CAF-1). Recent studies support a model in which CAF-1 can be targeted to newly synthesized DNA through a direct interaction with proliferating cell nuclear antigen (PCNA) and can act synergistically with a newly identified histone chaperone. Insights have also been obtained into mechanisms by which this CAF-1-dependent pathway can establish a repressed chromatin state.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Genet. Dev.
    Title
    Current Opinion in Genetics and Development
    Publication Year
    1991-
    ISBN/ISSN
    0959-437X
    Data From Reference
    Genes (10)