Beller, M., Blanke, S., Brentrup, D., Jäckle, H. (2002). Identification and expression of Ima, a novel Ral-interacting Drosophila protein.  Mech. Dev. 119(Suppl. 1): S253--S260.

FBrf0161469

Research paper

We report the identification of Ima, a novel Drosophila MAGUK-like protein, which contains two WW and four PDZ protein interaction domains and interacts with the small GTPase dRal in the yeast two-hybrid system and pull-down assays. The gene is expressed in distinct spatiotemporal patterns throughout embryonic development. Overexpression of Ima interferes with normal Drosophila development, indicating that the gene functions in a tissue specific manner.