Abstract
Centrioles are remarkably stable organelles that play a main role in the assembly of centrosomes and ciliary structures. However, there are several differentiated tissues that must eliminate their centrioles to avoid centrosome formation and improper cell proliferation. Therefore, centriole elimination represents an important process in many organisms to ensure successful cell differentiation and maintenance of tissue homeostasis. In this review, we analyzed centriole inactivation and elimination in various Drosophila cell types in relation to the dynamics of the pericentriolar material.
