Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\asl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\asl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
asl protein is closely associated with the centriole wall, but is not part of the centriole structure.
asl is involved in centriole duplication and is required for efficient recruitment of pericentriolar material.
Expression is enriched in embryonic gonads.
Identification: in a genetic screen for mutants defective in mechanosensation.
Mutants have severe defects in mechanosensory transduction.
Mutants are male sterile with no spindle aster in primary spermatocytes.