FB2026_02 , released June 18, 2026
Allele: Dmel\ppl00217
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General Information
Symbol
Dmel\ppl00217
Species
D. melanogaster
Name
FlyBase ID
FBal0009371
Feature type
allele
Associated gene
Dmel\ppl
Associated Insertion(s)
P{PZ}ppl00217
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Zinke et al., 1999)
Mutagen
P-element activity
(Spradling et al., 1999, Zinke et al., 1999, FlyBase, 1996-, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}ppl00217
Cytology
Description

P{PZ} is inserted 451bp downstream of ppl.

(Zinke et al., 1999)

The P{PZ}ppl00217 insertion is identified as an allele of ppl on genetic grounds (see FBrf0112101) as well as an allele of AcCoAS on molecular grounds (it is within the AcCoAS transcription unit).

(FlyBase, 1996-)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Food remains in the pharynx of mutant animals and does not move from the pharynx into the esophagus.

      (Zinke et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      ppl[+]/ppl00217 is an enhancer of wing margin phenotype of Bx2

      (Bronstein et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      ppl06913

      (Zinke et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Excision of the insertion reverts the lethal phenotype.

      (Zinke et al., 1999)

      Complements: l(3)0761507615. Complements: l(3)j1B10j1B10. Complements: l(3)j2C4j2C4. Complements: l(3)neo291.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      l(3)00217
      (Spradling et al., 1999)
      l(3)78Cb00217
      (BDGP Project Members, 1994-1999)
      ppl-00217
      (Zinke et al., 1999)
      ppl00217
      (Bronstein et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)