FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rm6201086
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General Information
Symbol
Dmel\Rm6201086
Species
D. melanogaster
Name
FlyBase ID
FBal0009400
Feature type
allele
Associated gene
Dmel\Rm62
Associated Insertion(s)
P{PZ}Rm6201086
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{PZ}Rm6201086
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rm62CB02119/Rm6201086 mutant flies infected with the bunyavirus Rift Valley Fever Virus (RVFV) exhibit a dramatic increase in mortality compared to sibling controls. The survival of uninfected flies is unaffected. Increased mortality is also seen when Rm62CB02119/Rm6201086 mutant flies are infected with another bunyavirus, La Crosse Virus (LACV). No increase in mortality is seen with Drosophila C virus (DCV), Vesicular stomatitis virus (VSV) or Sindbis virus (SINV) infection.

      (Moy et al., 2014)

      Rm6201086 heterozygotes do not display any significant decrease in viability relative to controls.

      (Qurashi et al., 2011)

      3% of heterozygous males show transformation of abdominal segment A6 into A5. Transformation of haltere into wing or transformation of T3 or T2 legs into T1 identity is not seen.

      (Lamiable et al., 2010)

      The rough eye phenotype observed in Fmr1sev.PW flies is suppressed in a Rm6201086/+ background.

      (Cziko et al., 2009)

      Rm62CB02119/Rm6201086 adults have reduced, thin, or missing dorsocentral and scutellar bristles. Rm62CB02119/Rm6201086 females are sterile; the nurse cell chromosomes of the follicles of these female mutants fails to disperse during the fifth endocycle and these follicles have degenerated by stage 8.

      (Buszczak and Spradling, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Rm62[+]/Rm6201086 is an enhancer of eye phenotype of Scer\GAL4GMR.PU, Zzzz\CGG90.UAS.EGFP

      (Qurashi et al., 2011)

      Rm62[+]/Rm6201086 is an enhancer of ommatidium | adult stage phenotype of Scer\GAL4GMR.PU, Zzzz\CGG90.UAS.EGFP

      (Qurashi et al., 2011)

      Rm62[+]/Rm6201086 is an enhancer of interommatidial bristle | adult stage phenotype of Scer\GAL4GMR.PU, Zzzz\CGG90.UAS.EGFP

      (Qurashi et al., 2011)

      Rm62[+]/Rm6201086 is an enhancer of mesothoracic leg phenotype of Pc1

      (Lamiable et al., 2010)

      Rm62[+]/Rm6201086 is an enhancer of metathoracic leg phenotype of Pc1

      (Lamiable et al., 2010)

      Rm62[+]/Rm6201086 is an enhancer of sex comb | ectopic phenotype of Pc1

      (Lamiable et al., 2010)
      Suppressor of
      Statement
      Reference

      Rm62[+]/Rm6201086 is a suppressor of eye phenotype of Fmr1sev.PW

      (Cziko et al., 2009)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      1.3% of Dsp11/Y ; Rm6201086/+ males show transformation of haltere into wing. 38% of these males show transformation of abdominal segment A6 into A5.

      7.7% of Rm6201086/trxE2 double heterozygous males show transformation of abdominal segment A6 into A5. 6.6% of the double heterozygotes show transformation of haltere into wing.

      95% of Pc1/Rm6201086 double heterozygous males show transformation of T3 or T2 legs into T1 identity.

      (Lamiable et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference

      The eye degeneration phenotype (rough eye with disorganized ommatidial lattice and interommatidial bristles) characteristic for flies expressing Zzzz\CGG90.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4GMR.PU is significantly worsened by combination with a single copy of Rm6201086.

      (Qurashi et al., 2011)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: casneo33.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      Lip01086
      Rm6201084
      (Qurashi et al., 2011)
      Rm6201086
      (Shun Li et al., 2025, Liaw and Chiang, 2019, Moy et al., 2014, Li et al., 2013, Lamiable et al., 2010)
      l(3)01086
      (Spradling et al., 1999)
      l(3)0108601086
      rm62P<up>01086</up>
      (Cziko et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (13)