FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\qua9
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General Information
Symbol
Dmel\qua9
Species
D. melanogaster
Name
FlyBase ID
FBal0014162
Feature type
allele
Associated gene
Dmel\qua
Associated Insertion(s)
Carried in Construct
Also Known As
quaHM14
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Cant et al., 1998, Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Apoptotic nuclei are seen in qua9 egg chambers, although the pattern of apoptosis appears somewhat different to wild-type.

      (Cavaliere et al., 1998)

      Does not show premature cytoplasmic streaming in stage 8 egg chambers.

      (Manseau et al., 1996)

      Stage 14 egg chambers of homozygous mothers exhibit short dorsal filaments.

      (Rittenhouse and Berg, 1995)

      Females are slightly fertile, oocytes produced are 75% normal size.

      (Mahajan-Miklos and Cooley, 1994)

      Eggs are tiny due to a failure to transport nurse cell content into the oocyte.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      qua9, snG409E has female sterile phenotype

      (Cant et al., 1998)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      qua9 is an enhancer of nurse cell phenotype of snG409E

      (Cant et al., 1998)
      NOT Enhancer of
      Statement
      Reference

      qua[+]/qua9 is a non-enhancer of phenotype of ctL188

      (Jackson and Berg, 1999)

      qua[+]/qua9 is a non-enhancer of phenotype of ctC145

      (Jackson and Berg, 1999)

      qua9 is a non-enhancer of phenotype of ctC145

      (Jackson and Berg, 1999)
      Suppressor of
      Statement
      Reference

      qua[+]/qua9 is a suppressor of mitotic domain 1 | embryonic cycle 14 phenotype of CycB+t10

      (Ji et al., 2002)
      NOT Suppressor of
      Statement
      Reference

      qua[+]/qua9 is a non-suppressor of aster | embryonic cycle 5 phenotype of CycB+t10

      (Ji et al., 2002)

      qua[+]/qua9 is a non-suppressor of aster | embryonic cycle 6 phenotype of CycB+t10

      (Ji et al., 2002)

      qua[+]/qua9 is a non-suppressor of aster | embryonic cycle 7 phenotype of CycB+t10

      (Ji et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Enhances the snG409E oogenesis phenotype; snG409E single mutant females are fertile, but snG409E/snG409E; qua9/+ females are weakly fertile and produce approximately 20% of the amount of progeny produced by snG409E single mutant females. Females doubly homozygous for snG409E and qua9 are completely sterile. The fertility of qua9 single mutant homozygotes is not affected by one copy of snG409E.

      (Cant et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Schupbach and Wieschaus.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (8)