The severity of wing defects caused by expression of sdScer\UAS.cVa under the control of Scer\GAL4vg.int2.1 is suppressed by sd58d/+; in the double mutant flies 61% have a "mild" phenotype (wings are significantly reduced, few veins and crossveins are still distinguishable), 34% have a "severe" phenotype (wing blade growth is severely impaired) and 5% have an "extreme" phenotype (thorax flight appendages are completely missing and no hinge structures are present).
Dorsal medial muscles in sd58d mutants display no obvious phenotype.
Mutant wing discs show a lower number of mitotically active cells, as well as a smaller wing pouch. Mutant animals small malformed small wings.
Mutant animals show extensive loss of wing tissue and diminutive halteres.
In developing imaginal discs, sd58d mutant clones can sometimes be recovered even 4 days after clone induction in proximal regions of the wing blade, but not in distal regions.
Ectopic bristles on the distal wing blade.
Incomplete penetrance of the nibbled wing margin phenotype. Ectopic bristles are never seen on the wing veins.
Wings reduced to vestiges, like vg. Halteres and bristles also like vg. sd58d/sd has strap-shaped wing. Temperature sensitive; effects of temperature pulses at different developmental stages suggest that wing areas eliminated in a specific order (Simpson, Lawrence and Maschat, 1981). RK2A.