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General Information
Symbol
Dmel\astK6
Species
D. melanogaster
Name
FlyBase ID
FBal0062965
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a P-element 20bp upstream of the transcription start site.

P-element insertion 1.6kb to the right of coordinate -5.0.

Insertion components
P{}astK6
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygotes have normal eyes.

Transheterozygotes with ast1 exhibit disranged ommatidia in nearly wild-type sized eyes. No wing vein abnormalities are found.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

astK6/ast[+] is an enhancer of visible | dominant phenotype of S54

astK6/ast[+] is an enhancer of visible | dominant phenotype of EgfrE1

astK6/ast[+] is an enhancer of visible phenotype of S1

astK6/ast[+] is an enhancer of visible phenotype of SL

Phenotype Manifest In
Enhancer of
Statement
Reference

astK6/ast[+] is an enhancer of eye phenotype of S54

astK6/ast[+] is an enhancer of eye phenotype of SL

astK6/ast[+] is an enhancer of ommatidium phenotype of S54

astK6/ast[+] is an enhancer of eye phenotype of EgfrE1

astK6/ast[+] is an enhancer of ommatidium phenotype of EgfrE1

astK6/ast[+] is an enhancer of eye phenotype of S1

NOT Enhancer of
Statement
Reference

astK6 is a non-enhancer of phenotype of rhove-1

astK6 is a non-enhancer of phenotype of ro1

Additional Comments
Genetic Interactions
Statement
Reference

Dominantly enhances the eye phenotype of S54, S1, SL, Df(2L)S3, Df(2L)ast2 and EgfrE1. Double heterozygotes with spi1, rhove-1, Df(3R)by10 or sim1 do not have a visible phenotype. Does not dominantly alter the phenotype of ro1 or rhove-1 homozygotes. sim1/astK6 double heterozygotes do not have a visible phenotype.

Heterozygotes with S1 are viable.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Class 1 ast mutation.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
astK6
Name Synonyms
Secondary FlyBase IDs
    References (2)