FlyBase Allele Report: Scer\GAL4[Eh.2.4]

General Information

Symbol

Scer\GAL4^Eh.2.4

Species

S. cerevisiae

Name

FlyBase ID

FBal0083453

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GAL4-Eh.2.4}

Also Known As

EH-GAL4, EHups-GAL4, Eh^ups-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(McNabb et al., 1997)

Progenitor genotype

Carried in construct

P{GAL4-Eh.2.4}

Cytology

Description

A 2.4kb SalI-XbaI fragment including the Eh transcriptional start site and extending upstream from it regulates expression of a GAL4 driver.

(McNabb et al., 1997)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 17 -- wandering third instar larval stage

neuron | subset

(McNabb et al., 1997)

brain | restricted

(McNabb et al., 1997)

neuron of brain | subset

(McNabb et al., 1997)

larval stage -- pupal stage

larval Eh neurosecretory neuron

(Grönke et al., 2009)

larval stage -- adult stage

neuron of brain | subset

(Clark et al., 2002)

brain | restricted

(Clark et al., 2002)

neuron | subset

(Clark et al., 2002)

pupal stage

neuron of central nervous system | subset

(Baker et al., 1999)

central nervous system | restricted

(Baker et al., 1999)

neuron | subset

(Baker et al., 1999)

pharate adult stage P14 -- P15

pupal Pdf neuron close to tritocerebrum

(Selcho et al., 2018)

Additional Information

Statement

Reference

Drives expression in eclosion hormone neurons.

(FlyBase Curators, 2017)

Expression is observed in eclosion-hormone expressing neurons.

(Clark et al., 2002)

Expression is observed in eclosion hormone-expressing neurons.

(Baker et al., 1999)

Late third instar larval expression is observed in two neurons, the eclosion hormone neurons, in the brain lobes. A representative image can be seen in FBrf0098847.

(McNabb et al., 1997)

Marker for

Reflects expression of

(Grönke et al., 2009, Clark et al., 2002, Baker et al., 1999, McNabb et al., 1997)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult cuticle, with lark^UAS.Tag:HA

(Schroeder et al., 2003)

adult cuticle, with nanos^{αTub84B.3'UTR.nanos+2.UAS}

(Clark et al., 2002)

adult cuticle, with nanos^{αTub84B.3'UTR.UAS}

(Clark et al., 2002)

adult cuticle, with rpr^UAS.cZa

(McNabb et al., 1997)

embryonic/larval mouth, with rpr^UAS.cZa

(Clark et al., 2004)

embryonic/larval mouth, with Scer\GAL4^CCAP.PP, rpr^UAS.cZa

(Clark et al., 2004)

embryonic/larval tracheal section | dorsal, with hid^UAS.cZa

(McNabb et al., 1997)

embryonic/larval tracheal section | dorsal, with rpr^UAS.cZa

(McNabb et al., 1997)

larval Eh neurosecretory neuron, with rpr^UAS.cZa

(Kim et al., 2006, Clark et al., 2004)

neuron | larval stage, with hid^UAS.cZa

(McNabb et al., 1997)

neuron | larval stage, with rpr^UAS.cZa

(McNabb et al., 1997)

wing, with lark^UAS.Tag:HA

(Schroeder et al., 2003)

wing, with nanos^{αTub84B.3'UTR.nanos+2.UAS}

(Clark et al., 2002)

wing, with nanos^{αTub84B.3'UTR.UAS}

(Clark et al., 2002)

wing, with rpr^UAS.cZa

(McNabb et al., 1997)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Eh.2.4/Eh^UAS.cKa rescues Eh^exc/Df(3R)Eh

(Krüger et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

6301

108731

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^Eh.2.4

Scer\GAL4^Eh.2.4

Name Synonyms

Secondary FlyBase IDs

References (24)

Report Sections

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