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General Information
Symbol
Dmel\fjN7
Species
D. melanogaster
Name
FlyBase ID
FBal0127230
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the P{lacW} element, resulting in a complex rearrangement that retains the Ecol\lacZ marker gene.

Insertion components
P{?lacW}fjN7
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

An equator can easily be discerned in fjd1/fjN7 eyes. 98.5% of ommatidia are correctly constructed and rotated in these animals. Flies expressing fjScer\UAS.cZa under the control of Scer\GAL4αTub84B.PL in a fjd1/fjN7 background have a normal overall pattern of polarisation in the eye; an equator can easily be discerned. 92.9% of ommatidia are correctly constructed and rotated in these animals. Expression of fjScer\UAS.cZa under the control of Scer\GAL4bi-omb3-GAL4 in a fjd1/fjN7 background has a profound effect on ommatidial polarity; near the dorsal pole, large-scale reversals of ommatidial polarity are seen.

When homozygous mutant clones are made specifically in the equatorial R3/R4 precursor, most (71%) of the consequent ommatidia are in the reverse polarity. When clones are made specifically in the polar R3/R4 precursor, almost all (94%) of the consequent ommatidia are in the wild-type polarity. The mutant photoreceptor precursor eventually becomes an R4 photoreceptor 84% of the time (50% in wild-type).

The joint between tarsal segments 2 and 3 is incomplete in 96.7% of cases and fused in 3.3% of cases in homozygous flies.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

fjN7 has visible phenotype, enhanceable by +/Df(3L)st-j7

fjN7 has visible phenotype, enhanceable by d210/d[+]

fjN7 has visible phenotype, enhanceable by SerCS94/Ser[+]

fjN7 has visible phenotype, enhanceable by Ser[+]/SerRX106

fjN7 has visible phenotype, enhanceable by ena[+]/ena210

fjN7 has visible phenotype, enhanceable by ena23/ena[+]

Other
Phenotype Manifest In
Enhanced by
Statement
Reference

fjN7 has joint phenotype, enhanceable by +/Df(3L)st-j7

fjN7 has joint phenotype, enhanceable by d210/d[+]

fjN7 has joint phenotype, enhanceable by SerCS94/Ser[+]

fjN7 has joint phenotype, enhanceable by Ser[+]/SerRX106

fjN7 has joint phenotype, enhanceable by ena[+]/ena210

fjN7 has joint phenotype, enhanceable by ena23/ena[+]

Suppressor of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

ds38k fjN7/dsUAO71 fjd1 flies have disorganised ommatidial polarity; no obvious equator is present. Flies expressing both fjScer\UAS.cZa and dsScer\UAS.P\T.cSa under the control of Scer\GAL4αTub84B.PL in a ds38k fjN7/dsUAO71 fjd1 background have a disorganised ommatidial polarity; no obvious equator is present. Flies expressing dsScer\UAS.P\T.cSa under the control of Scer\GAL4αTub84B.PL in a ds38k fjN7/dsUAO71 fjd1 background have a disorganised ommatidial polarity; no obvious equator is present. Flies expressing fjScer\UAS.cZa under the control of Scer\GAL4αTub84B.PL in a ds38k fjN7/dsUAO71 fjd1 background have a disorganised ommatidial polarity; no obvious equator is present. Flies expressing dsScer\UAS.P\T.cSa under the control of Scer\GAL4fj-VG1 in a dsUAO71 fjVG1/ds38k fjN7 background have a disorganised ommatidial polarity; the eye contains a clearly perceptible equator in which most of the nearby ommatidia are reversed in polarity and thus point away from the equator. The polarity reversals in the eye seen in flies expressing ftScer\UAS.P\T.cSa under the control of Scer\GAL4bi-omb3-GAL4 is strengthened in a fjN7/fjd1 background. Flies expressing both fjScer\UAS.cZa and dsScer\UAS.P\T.cSa under the control of Scer\GAL4αTub84B.PL in a ds38k fjN7/dsUAO71 fjd1 background have normal polarity throughout the wing blade with the exception of a small region along the anterior proximal margin of the wing, where a small swirl is often present. Flies expressing dsScer\UAS.P\T.cSa under the control of Scer\GAL4αTub84B.PL in a ds38k fjN7/dsUAO71 fjd1 background have normal polarity throughout the wing blade with the exception of a small region along the anterior proximal margin of the wing, where a small swirl is often present.

When dsUAO71 homozygous mutant clones are made specifically in the equatorial R3/R4 precursors of fjN7 mutant flies, almost all (92%) of the consequent ommatidia are in the wild-type polarity. When clones are made specifically in the polar R3/R4 precursor, most (73%) of the consequent ommatidia are in the reverse polarity. The mutant photoreceptor precursor eventually becomes an R3 photoreceptor 85% of the time (50% in wild-type).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)