FlyBase Allele Report: Scer\GAL4[Ilp2.PW]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^Ilp2.PW

General Information

Symbol

Scer\GAL4^Ilp2.PW

Species

S. cerevisiae

Name

FlyBase ID

FBal0191778

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

dilp2-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Wu et al., 2005)

Progenitor genotype

Carried in construct

Cytology

Description

2kb of the Ilp2 promoter control expression of a GAL4 driver.

(Wu et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

Ilp2_2.0kb-Gal4

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult insulin secreting cell of pars intercerebralis | subset

(Enell et al., 2010)

adult pars intercerebralis

(Enell et al., 2010)

adult median bundle | dorsal

(Enell et al., 2010)

(Enell et al., 2010)

adult insulin secreting cell of pars intercerebralis

(Luo et al., 2012)

Additional Information

Statement

Reference

Serotonergic neuron branches can be found close to neuron branches of the ScerGAL4^Ilp2.PW-positive insulin secreting cells of the pars intercerebralis.

(Luo et al., 2012)

ScerGAL4^Ilp2.PW drives expression in the insulin producing cells (IPC cells) of the pars intercerebralis. These cells comprise a dorsal subset of the median neurosecretory cells. Expression of ScerGAL4^Ilp2.PW is found in their arborisations along the median bundle and in the tritocerebrum. Puncta of GABA-B-R2 protein are visible in the arborisation of the IPC cells, co-localising with ScerGAL4^Ilp2.PW expression.

(Enell et al., 2010)

Marker for

Reflects expression of

(Luo et al., 2012, Enell et al., 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body size, with Rab1^S25N.UAS.YFP

(Cao et al., 2014)

abnormal body size, with unc-104^GD13526

(Cao et al., 2014)

abnormal body size, with unc-104^HM05162

(Cao et al., 2014)

abnormal cold stress response, with 5-HT1A^KK108407

(Luo et al., 2012)

abnormal cold stress response, with 5-HT1A^RNAi.UAS

(Luo et al., 2012)

abnormal developmental rate, with Rab1^S25N.UAS.YFP

(Cao et al., 2014)

abnormal developmental rate, with unc-104^GD13526

(Cao et al., 2014)

abnormal feeding behavior, with S6k^KQ.UAS

(Wu et al., 2005)

abnormal feeding behavior, with S6k^STDE.UAS

(Wu et al., 2005)

abnormal heat stress response, with 5-HT1A^KK108407

(Luo et al., 2012)

abnormal neuroanatomy | larval stage, with Rab1^S25N.UAS.YFP

(Cao et al., 2014)

abnormal neuroanatomy | larval stage, with unc-104^GD13526

(Cao et al., 2014)

abnormal starvation stress response, with 5-HT1A^KK108407

(Luo et al., 2012)

abnormal starvation stress response, with 5-HT1A^RNAi.UAS

(Luo et al., 2012)

abnormal starvation stress response, with 5-HT7^UAS.cKa

(Luo et al., 2012)

short lived, with 5-HT1A^KK108407

(Luo et al., 2012)

short lived, with 5-HT1A^RNAi.UAS

(Luo et al., 2012)

short lived, with 5-HT7^UAS.cKa

(Luo et al., 2012)

short lived | nutrition conditional, with GABA-B-R2^KK100020

(Enell et al., 2010)

short lived | nutrition conditional, with GABA-B-R2^RNAi.UAS

(Enell et al., 2010)

short lived | nutrition conditional, with Ilp2^UAS.cBa

(Enell et al., 2010)

short lived | nutrition conditional, with Irk3^GD1764

(Enell et al., 2010)

short lived | nutrition conditional, with Irk3^KK107031

(Enell et al., 2010)

viable, with Gp93^NIG.5520R

(Maynard et al., 2010)

Phenotype Manifest In

dendrite, with Rab1^S25N.UAS.YFP

(Cao et al., 2014)

larval insulin secreting cell of pars intercerebralis, with Rab1^S25N.UAS.YFP

(Cao et al., 2014)

larval insulin secreting cell of pars intercerebralis, with unc-104^GD13526

(Cao et al., 2014)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^Ilp2.PW

Scer\GAL4^Ilp2

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections