FlyBase Allele Report: Dmel\Gp93[NIG.5520R]

General Information

Symbol

Dmel\Gp93^NIG.5520R

Species

D. melanogaster

Name

FlyBase ID

FBal0244043

Feature type

allele

Associated gene

Dmel\Gp93

Associated Insertion(s)

Carried in Construct

P{NIG.5520R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Maynard et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Maynard et al., 2010)

Mutagen

in vitro construct

(Maynard et al., 2010)

Progenitor genotype

Carried in construct

P{NIG.5520R}

Cytology

Description

UASt regulatory sequences drive expression of a hairpin of Gp93 sequence.

(Maynard et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-5520R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased rate of adult locomotory behavior | adult stage, with Scer\GAL4^elav.PLu

(Xu et al., 2025)

decreased size | adult stage, with Scer\GAL4^elav.PLu

(Xu et al., 2025)

decreased size | adult stage, with Scer\GAL4^ey.3.5.Exel

(Xu et al., 2025)

decreased size | adult stage, with Scer\GAL4^nub.PU

(Xu et al., 2025)

increased cell death | larval stage, with Scer\GAL4^ey.3.5.Exel

(Xu et al., 2025)

increased cell death | larval stage, with Scer\GAL4^GMR.PU

(Xu et al., 2025)

increased cell death | larval stage, with Scer\GAL4^nub.PU

(Xu et al., 2025)

increased cell death | larval stage, with Scer\GAL4^ptc.PU

(Xu et al., 2025)

viable, with Scer\GAL4^Ilp2.PW

(Maynard et al., 2010)

visible | adult stage, with Scer\GAL4^ey.3.5.Exel

(Xu et al., 2025)

visible | adult stage, with Scer\GAL4^nub.PU

(Xu et al., 2025)

Phenotype Manifest In

adult brain, with Scer\GAL4^elav.PLu

(Xu et al., 2025)

embryonic/larval copper cell, with Scer\GAL4^mex1.2.1

(Maynard et al., 2010)

eye, with Scer\GAL4^ey.3.5.Exel

(Xu et al., 2025)

eye-antennal disc | larval stage, with Scer\GAL4^ey.3.5.Exel

(Xu et al., 2025)

eye-antennal disc | larval stage, with Scer\GAL4^GMR.PU

(Xu et al., 2025)

vacuole | increased number, with Scer\GAL4^elav.PLu

(Xu et al., 2025)

wing, with Scer\GAL4^nub.PU

(Xu et al., 2025)

wing disc | larval stage, with Scer\GAL4^nub.PU

(Xu et al., 2025)

wing disc | larval stage, with Scer\GAL4^ptc.PU

(Xu et al., 2025)

Detailed Description

Statement

Reference

Expression of Gp93^NIG.5520R under the control of Scer\GAL4^mex1.2.1 severely affects the morphology of copper cells in the midgut of male larvae.

Animals expressing Gp93^NIG.5520R under the control of Scer\GAL4^Ilp2.PW progress to adulthood with no discernible defects.

(Maynard et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Gtpx^G7172, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Gtpx^G7172, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Sod1^UAS.cAa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Sod1^UAS.cAa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Gtpx^G7172, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by PEK^GD5584, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by PEK^KK100348, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has decreased rate of adult locomotory behavior | adult stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Dronc^DN.UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Dronc^DN.UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has decreased rate of adult locomotory behavior | adult stage phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Hsap\HSP90B1^UAS.Tag:MYC, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by Hsap\HSP90B1^UAS.Tag:MYC, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Hsap\HSP90B1^UAS.Tag:MYC, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by Dronc^DN.UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has increased cell death | larval stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, suppressible by Sod1^UAS.cAa, Scer\GAL4^nub.PU

(Xu et al., 2025)

NOT suppressed by

Statement

Reference

Gp93^NIG.5520R, Scer\GAL4^nub.PU has visible | adult stage phenotype, non-suppressible by Hsp83^UAS.cZa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has decreased size | adult stage phenotype, non-suppressible by Hsp83^UAS.cZa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Dronc^DN.UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Dronc^DN.UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Gtpx^G7172, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Sod1^UAS.cAa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Gtpx^G7172, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Sod1^UAS.cAa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Hsc70-3^UAS.cEa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by PEK^KK100348, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by PEK^GD5584, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has adult brain phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has vacuole | increased number phenotype, suppressible by puc^UAS.cMa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has adult brain phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^elav.PLu has vacuole | increased number phenotype, suppressible by Hsap\SOD1^UAS.cUa, Scer\GAL4^elav.PLu

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, suppressible by Hsap\HSP90B1^UAS.Tag:MYC, Scer\GAL4^nub.PU

(Xu et al., 2025)

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing disc | larval stage phenotype, suppressible by Hsap\HSP90B1^UAS.Tag:MYC, Scer\GAL4^nub.PU

(Xu et al., 2025)

NOT suppressed by

Statement

Reference

Gp93^NIG.5520R, Scer\GAL4^nub.PU has wing phenotype, non-suppressible by Hsp83^UAS.cZa, Scer\GAL4^nub.PU

(Xu et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Gp93^NIG.5520R is rescued by Scer\GAL4^ey.PH/Gp93^GS16347

(Xu et al., 2025)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

5520R-1

P{NIG.5520R}1

5520R-3

P{NIG.5520R}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Gp93^NIG.5520R

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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