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General Information
Symbol
Dmel\CtBPGSA396
Species
D. melanogaster
Name
FlyBase ID
FBal0194801
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{GSV1} insertion in the first intron of CtBP.

Insertion components
P{GSV1}CtBPGSA396
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of CtBPGSA396 under the control of Scer\GAL4ey.PU leads to small and rough eyes with duplications of interommatidial bristles; occasional splitting of the eye field, sometimes accompanied by formation of antennal-like structures in the cuticular field between eye domains; apparent clefts in the vertex region of the head with loss of ocelli and mispatterning of bristles; loss of vibrissae and replacement by bristles resembling orbital or vertical bristles; and extra orbital bristles surrounded by a patch of orbital-like cuticle; and in few animals loss of distal antennal structures when compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has visible | adult stage phenotype, enhanceable by eya2015/eya[+]

NOT Enhanced by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has abnormal size | adult stage phenotype, non-enhanceable by so[+]/so3

CtBPGSA396, Scer\GAL4ey.PU has visible | adult stage phenotype, non-enhanceable by so[+]/so3

Suppressed by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has visible | adult stage phenotype, suppressible | partially by dacP/dac[+]

NOT suppressed by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has abnormal size | adult stage phenotype, non-suppressible by so[+]/so3

CtBPGSA396, Scer\GAL4ey.PU has visible | adult stage phenotype, non-suppressible by so[+]/so3

Phenotype Manifest In
Enhanced by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, enhanceable by eya2015/eya[+]

NOT Enhanced by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, non-enhanceable by so[+]/so3

Suppressed by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, suppressible | partially by ey+/ey2

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, suppressible | partially by eyR/ey+

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, suppressible | partially by dacP/dac[+]

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, suppressible | partially by danems3/dan[+]

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, suppressible | partially by danr[+]/danrex35

NOT suppressed by
Statement
Reference

CtBPGSA396, Scer\GAL4ey.PU has eye phenotype, non-suppressible by so[+]/so3

Suppressor of
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Coexpression of CtBPGSA396, suppress the eye phenotype of Scer\GAL4GMR.PF>wgScer\UAS.cKa flies. Expression of CtBPGSA396 under the control of Scer\GAL4GMR.PF also suppresses the eye phenotype of armS56F.GMR flies. However, expression of this transgene fails to suppress the small eye phenotype generated by WGMR.PG.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
CtBPGSA396
Name Synonyms
Secondary FlyBase IDs
    References (2)