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General Information
Symbol
Dmel\dacP
Species
D. melanogaster
Name
FlyBase ID
FBal0009297
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dac-lacZ
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion 11bp downstream of the putative dac transcription start site.

P element inserted 11bp after the start of transcription.

Insertion components
P{PZ}dacP
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

dacP heterozygotes do not exhibit any size alterations or roughness in eyes when compared to control adults.

Homozygous adults have a mild mushroom body phenotype. The eyes are consistently (but less severely than ey2) reduced in size.

Eyes of homozygotes are reduced and roughened. 50% of ommatidia have either too many or too few photoreceptors, and the ommatidial array is disrupted. Morphogenetic furrow movement is uneven, resulting in a curved furrow that has advanced further at midline than at the periphery of the disc. While legs have normal proximal and distal morphology, femur, tibia and proximal three tarsi are fused and condensed.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

dacP has visible phenotype, enhanceable by ey2/ey2

dacP has visible | recessive phenotype, enhanceable by hh[+]/hhrJ413

Enhancer of
Statement
Reference

dacP/dacP is an enhancer of visible phenotype of ey2

Suppressor of
Statement
Reference

dacP/dac[+] is a suppressor | partially of visible | adult stage phenotype of CtBPGSA396, Scer\GAL4ey.PU

dacP/dac[+] is a suppressor of visible | heat sensitive phenotype of peb1

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

dacP has eye phenotype, enhanceable by ey2/ey2

dacP has eye phenotype, enhanceable by hh[+]/hhrJ413

NOT Enhanced by
Statement
Reference

dacP has phenotype, non-enhanceable by ey[+]/eyD1Da

dacP has mushroom body phenotype, non-enhanceable by ey[+]/eyD1Da

dacP has phenotype, non-enhanceable by ey[+]/eyJD

dacP has mushroom body phenotype, non-enhanceable by ey[+]/eyJD

dacP has phenotype, non-enhanceable by ey2/ey2

dacP has mushroom body phenotype, non-enhanceable by ey2/ey2

Enhancer of
Statement
Reference

dacP/dacP is an enhancer of eye phenotype of ey2

Suppressor of
Statement
Reference

dacP/dac[+] is a suppressor | partially of eye phenotype of CtBPGSA396, Scer\GAL4ey.PU

dacP/dac[+] is a suppressor of eye | heat sensitive phenotype of peb1

dacP is a suppressor of phenotype of EgfrE3

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The eyes of dacP; ey2 double homozygotes are consistently very small or absent.

Suppresses the rough eye phenotype of EgfrE3. dacP, Egfrt1 double homozygotes have a reduced, rough eye phenotype that exceeds that of either mutant alone or the expected additive effects of the two mutants. hhrJ413 dominantly enhances the recessive eye phenotype of dacP.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

G. Rubin.

Comments
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (14)