Expression of zipGD1566 under the control of Scer\GAL4hth-GETDB in the larval antennal disc leads to disorganization and a breakdown of the field boundary at the A1 fold, in contrast to controls, and mislocalized cells are maintained and integrated in the epithelial sheet.
Eye-antennal disc clones expressing zipGD1566 under the control of Scer\GAL4tub.PU exhibit a small reduction in size as compared to wild type clones, along with some defects in differentiation and cell morphology.
Expression of zipGD1566 under the control of Scer\GAL4Act.PU in clones in the eye disc results in differentiation defects without inducing a cell invasion phenotype.
Expression under the control of Scer\GAL41407 results in an extreme increase in neuroblast size in the larval brain, without loss of neuroblasts.
Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.
Expression under the control of Scer\GAL41407 results in extreme defects in the shape of neuroblasts in the larval brain.
Adults expressing zipGD1566 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in adult/pharate lethality.