FlyBase Allele Report: Scer\GAL4[GSG2295]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^GSG2295

General Information

Symbol

Scer\GAL4^GSG2295

Species

S. cerevisiae

Name

FlyBase ID

FBal0220226

Feature type

allele

Associated gene

Associated Insertion(s)

P{Switch2}GSG2295

Carried in Construct

Also Known As

GSG2295-Gal4, GeneSwitch-Gal4-2295

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{Switch2}GSG2295

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

binary expression system - small molecule-regulated driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

Additional Information

Statement

Reference

ScerGAL4^GSG2295 drives primarily neuronal mifepristone-inducible expression. Weak expression is observed in ~3-8 ventral and/or lateral cells/hemisegment in the ventral nerve cord, and in a few scattered cells in the brain. Moderate expression is observed in the optic lobes. Strong expression is observed in class III and IV dendritic arborizing neurons (md-da). Variable expression is observed in occasional chordotonal organs. Expression is also observed in the gut. Weak uninduced expression is observed in a subset of CNS cells.

(Nicholson et al., 2008)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | pupal stage | RU486 conditional, with Patronin^{UAS.EGFP,Tag:HPC4}

(Wang et al., 2019)

abnormal neuroanatomy | P-stage | RU486 conditional, with chb^UAS.GFP

(Bu et al., 2022)

abnormal neuroanatomy | P-stage | RU486 conditional, with Efa6^VSH330083

(Bu et al., 2021)

abnormal neuroanatomy | P-stage | RU486 conditional, with stai^GL01099

(Bu et al., 2021)

abnormal neuroanatomy | P-stage | RU486 conditional, with Vps4^{DN.UAS.Tag:HA}

(Zhang et al., 2014)

abnormal neuroanatomy | pupal stage, with Rab1^S25N.UAS.YFP

(Wang et al., 2018)

abnormal neuroanatomy | pupal stage, with Sar1^T34N.UAS

(Wang et al., 2018)

abnormal neuroanatomy | pupal stage | RU486 conditional, with Arf1^Q71L.UAS.cWa

(Wang et al., 2017)

abnormal neuroanatomy | pupal stage | RU486 conditional, with Arf1^T31N.UAS.cWa

(Wang et al., 2017)

abnormal neuroanatomy | pupal stage | RU486 conditional, with Patronin^{UAS.EGFP,Tag:HPC4}

(Wang et al., 2019)

abnormal neuroanatomy | pupal stage | RU486 conditional, with Sec71^DN.UAS

(Wang et al., 2017)

abnormal neuroanatomy | pupal stage P5 | RU486 conditional, with unc-104^{AAA.UAS.Tag:HA}

(Zong et al., 2018)

abnormal neuroanatomy | pupal stage P5 | RU486 conditional, with unc-104^{G102E.UAS.Tag:HA}

(Zong et al., 2018)

abnormal size | pupal stage P5 | RU486 conditional, with unc-104^{AAA.UAS.Tag:HA}

(Zong et al., 2018)

abnormal size | pupal stage P5 | RU486 conditional, with unc-104^{G102E.UAS.Tag:HA}

(Zong et al., 2018)

Phenotype Manifest In

dendrite | P-stage | RU486 conditional, with chb^UAS.GFP

(Bu et al., 2022)

dendrite | P-stage | RU486 conditional, with Efa6^VSH330083

(Bu et al., 2021)

dendrite | P-stage | RU486 conditional, with stai^GL01099

(Bu et al., 2021)

dendrite | pupal stage | RU486 conditional, with Patronin^{UAS.EGFP,Tag:HPC4}

(Wang et al., 2019)

dendritic tree | P-stage | RU486 conditional, with Vps4^{DN.UAS.Tag:HA}

(Zhang et al., 2014)

dendritic tree | pupal stage, with Rab1^S25N.UAS.YFP

(Wang et al., 2018)

dendritic tree | pupal stage, with Sar1^T34N.UAS

(Wang et al., 2018)

dendritic tree | pupal stage | RU486 conditional, with Arf1^Q71L.UAS.cWa

(Wang et al., 2017)

dendritic tree | pupal stage | RU486 conditional, with Arf1^T31N.UAS.cWa

(Wang et al., 2017)

dendritic tree | pupal stage | RU486 conditional, with Sec71^DN.UAS

(Wang et al., 2017)

dendritic tree | pupal stage P5 | RU486 conditional, with unc-104^{AAA.UAS.Tag:HA}

(Zong et al., 2018)

dendritic tree | pupal stage P5 | RU486 conditional, with unc-104^{G102E.UAS.Tag:HA}

(Zong et al., 2018)

embryonic/larval sensory neuron | P-stage | RU486 conditional, with Efa6^VSH330083

(Bu et al., 2021)

embryonic/larval sensory neuron | P-stage | RU486 conditional, with stai^GL01099

(Bu et al., 2021)

endosome | P-stage | RU486 conditional, with Vps4^{DN.UAS.Tag:HA}

(Zhang et al., 2014)

Golgi apparatus | third instar larval stage | RU486 conditional, with Arf1^T31N.UAS.cWa

(Wang et al., 2017)

Golgi apparatus | third instar larval stage | RU486 conditional, with Sec71^DN.UAS

(Wang et al., 2017)

larval dorsal multidendritic neuron ddaC | P-stage | RU486 conditional, with chb^UAS.GFP

(Bu et al., 2022)

larval dorsal multidendritic neuron ddaC | P-stage | RU486 conditional, with Vps4^{DN.UAS.Tag:HA}

(Zhang et al., 2014)

larval dorsal multidendritic neuron ddaC | pupal stage, with Rab1^S25N.UAS.YFP

(Wang et al., 2018)

larval dorsal multidendritic neuron ddaC | pupal stage, with Sar1^T34N.UAS

(Wang et al., 2018)

larval dorsal multidendritic neuron ddaC | pupal stage | RU486 conditional, with Arf1^Q71L.UAS.cWa

(Wang et al., 2017)

larval dorsal multidendritic neuron ddaC | pupal stage | RU486 conditional, with Arf1^T31N.UAS.cWa

(Wang et al., 2017)

larval dorsal multidendritic neuron ddaC | pupal stage | RU486 conditional, with Patronin^{UAS.EGFP,Tag:HPC4}

(Wang et al., 2019)

larval dorsal multidendritic neuron ddaC | pupal stage | RU486 conditional, with Sec71^DN.UAS

(Wang et al., 2017)

larval dorsal multidendritic neuron ddaC | pupal stage P5 | RU486 conditional, with unc-104^{AAA.UAS.Tag:HA}

(Zong et al., 2018)

larval dorsal multidendritic neuron ddaC | pupal stage P5 | RU486 conditional, with unc-104^{G102E.UAS.Tag:HA}

(Zong et al., 2018)

larval dorsal multidendritic neuron ddaC | third instar larval stage | RU486 conditional, with Arf1^T31N.UAS.cWa

(Wang et al., 2017)

larval dorsal multidendritic neuron ddaC | third instar larval stage | RU486 conditional, with Sec71^DN.UAS

(Wang et al., 2017)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Sar1^UAS.ORF/Scer\GAL4^GSG2295 rescues Sar1^T34N.UAS

(Wang et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

40266

w^*; P{Switch2}GSG2295

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GSG2295

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections