Open Close
General Information
Symbol
Dmel\Sesnd04539
Species
D. melanogaster
Name
FlyBase ID
FBal0223949
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dSesnXP4
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{XP}Sesnd04539
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    When overexpressed in the dorsal wing epithelium under the control of Scer\GAL4ap-md544, Sesnd04539 reduces the growth of the target compartment, resulting in a slight bent-up wing phenotype.

    Overexpression of Sesnd04539 in dorsal cells of wings driven by Scer\GAL4ap-md544 results in a phenotype in which the wing bends upward. It appears that the suppressed tissue growth in the dorsal wing compartment results from a decrease in size of the constituent cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhanced by
    NOT Enhanced by
    Enhancer of
    Suppressor of
    NOT Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference
    NOT Enhanced by
    Statement
    Reference
    Enhancer of
    Suppressor of
    NOT Suppressor of
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Simultaneous expression of Sesnd04539 and gigScer\UAS.cKa using Scer\GAL4ap-md544 induces much more pronounced bent-up wing phenotype compared with the phenotype induce Sesnd04539 expression alone.

    Co-expression of Sesnd04539 with InRA1325D.Scer\UAS via Scer\GAL4GMR.PF suppresses the InRA1325D.Scer\UAS hyperplastic eye phenotype.

    Co-expression of Sesnd04539 with RhebScer\UAS.cPa via Scer\GAL4GMR.PF suppresses the RhebScer\UAS.cPa hyperplastic eye phenotype.

    Co-expression of Sesnd04539 with InRA1325D.Scer\UAS via Scer\GAL4ap-md544 suppresses the InRA1325D.Scer\UAS hyperplastic wing phenotype.

    Co-expression of Sesnd04539 with Pi3K92ECAAX.Scer\UAS via Scer\GAL4ap-md544 suppresses the Pi3K92ECAAX.Scer\UAS hyperplastic wing phenotype.

    Co-expression of Sesnd04539 with Akt1Scer\UAS.Exel via Scer\GAL4ap-md544 suppresses the Akt1Scer\UAS.Exel hyperplastic wing phenotype.

    Co-expression of Sesnd04539 with S6kSTDETE.Scer\UAS via Scer\GAL4ap-md544 fails to suppress the S6kSTDETE.Scer\UAS hyperplastic wing phenotype.

    Co-expression of Sesnd04539 with PtenScer\UAS.cGa driven by Scer\GAL4ap-md544 enhances the wing-bending phenotype of PtenScer\UAS.cGa.

    Co-expression of Sesnd04539 with InRK1409A.Scer\UAS driven by Scer\GAL4ap-md544 enhances the wing-bending phenotype of InRK1409A.Scer\UAS.

    Co-expression of Sesnd04539 with Pi3K92EA2860C.Scer\UAS driven by Scer\GAL4ap-md544 enhances the wing-bending phenotype of Pi3K92EA2860C.Scer\UAS.

    Co-expression of Sesnd04539 with S6kKQ.Scer\UAS driven by Scer\GAL4ap-md544 enhances the wing-bending phenotype of S6kKQ.Scer\UAS.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    CG11299d04539
    Sesnd04539
    Name Synonyms
    Secondary FlyBase IDs
      References (4)