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General Information
Symbol
Dmel\sdJF02514
Species
D. melanogaster
Name
FlyBase ID
FBal0242196
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-sdRNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of sdJF02514 under the control of Scer\GAL4GMR.PF (co-expressed with Dcr-2Scer\UAS.cDa) has no effect on eye disc apoptosis in third instar larvae.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Third instar larval eye-antennal imaginal disc clones co-expressing dlg1GD4689 and Ras85DV12.Scer\UAS under the control of Scer\GAL4Act5C.CoinFLP-FRT, in combination with Dicer-2 for efficient RNAi, form invasive tumors and induce autophagosomes (assessed by a Atg8a fluorescence reporter) in a cell non-autonomous manner in neighboring disc tissue, both of which are significantly suppressed by the additional clonal co-expression of sdJF02514.

Expression of sdJF02514 suppresses the cardiac hypertrophy seen when ykiS168A.Scer\UAS.T:SV5\V5 is expressed under the control of Scer\GAL4tin.CΔ4.

Expression of sdJF02514 (co-expressed with Dcr-2Scer\UAS.cDa) significantly suppresses the morphogenetic furrow cell death seen when exScer\UAS.cBa is expressed under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference

Expression of sdJF02514 does not suppress the cardiac hypertrophy seen in flies expressing Hsap\RAF1gof.Scer\UAS under the control of Scer\GAL4tin.CΔ4.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
sdJF02514
Name Synonyms
Secondary FlyBase IDs
    References (9)