FlyBase Allele Report: Scer\GAL4[ebd1.PB]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Scer\GAL4^ebd1.PB

General Information

Symbol

Scer\GAL4^ebd1.PB

Species

S. cerevisiae

Name

earthbound 1 promoter construct of Benchabane

FlyBase ID

FBal0258672

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Also Known As

ebd1-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Benchabane et al., 2011)

Progenitor genotype

Carried in construct

Cytology

Description

ebd1 regulatory sequences control expression of a GAL4 driver.

(Benchabane et al., 2011)

Amino acid replacement: R171C.

(Xin et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16

(Benchabane et al., 2011)

larval glial cell

(Benchabane et al., 2011)

larval central nervous system

(Benchabane et al., 2011)

larval muscle system

(Benchabane et al., 2011)

embryonic/larval garland cell

(Benchabane et al., 2011)

(Benchabane et al., 2011)

larval glial cell

(Benchabane et al., 2011)

larval central nervous system

(Benchabane et al., 2011)

larval muscle system

(Benchabane et al., 2011)

embryonic/larval salivary gland

(Benchabane et al., 2011)

adult salivary gland

(Benchabane et al., 2011)

dorsal longitudinal indirect flight muscle cell

(Benchabane et al., 2011)

Additional Information

Statement

Reference

Reporter expression recapitulates the ebd1 expression pattern. It is observed in embryos in neurons, glia, muscle cells, and garland cells. In larvae and pupae, expression persists in the same cell types and also in salivary glands. In pupae, the dorsal medial muscle fibres and myoblasts are stained.

(Benchabane et al., 2011)

Marker for

Reflects expression of

(Benchabane et al., 2011)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

flightless, with pan^ΔN.UAS

(Benchabane et al., 2011)

Phenotype Manifest In

dorsal longitudinal indirect flight muscle cell, with Axn^UAS.GFP

(Benchabane et al., 2011)

indirect flight muscle cell, with Axn^UAS.GFP

(Benchabane et al., 2011, Xin et al., 2011)

indirect flight muscle cell, with pan^ΔN.UAS

(Benchabane et al., 2011, Xin et al., 2011)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^ebd1.PB, pan^ΔN.UAS has flightless phenotype, suppressible by Scer\GAL4^ebd1.PB/arm^{S10.UAS.Tag:MYC}

(Benchabane et al., 2011)

Scer\GAL4^ebd1.PB, pan^ΔN.UAS has flightless phenotype, suppressible by Hsap\JRK^UAS.cBa, Scer\GAL4^ebd1.PB

(Benchabane et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^ebd1.PB/arm^{S10.UAS.Tag:MYC} is a suppressor of flightless phenotype of Scer\GAL4^ebd1.PB, pan^ΔN.UAS

(Benchabane et al., 2011)

Hsap\JRK^UAS.cBa, Scer\GAL4^ebd1.PB is a suppressor of flightless phenotype of Scer\GAL4^ebd1.PB, pan^ΔN.UAS

(Benchabane et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^ebd1.PB, pan^ΔN.UAS has indirect flight muscle cell phenotype, enhanceable by ewg[+]/ewg²

(Xin et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^ebd1.PB, pan^ΔN.UAS has indirect flight muscle cell phenotype, suppressible by Scer\GAL4^ebd1.PB/arm^{S10.UAS.Tag:MYC}

(Benchabane et al., 2011)

Scer\GAL4^ebd1.PB, pan^ΔN.UAS has indirect flight muscle cell phenotype, suppressible by Hsap\JRK^UAS.cBa, Scer\GAL4^ebd1.PB

(Benchabane et al., 2011)

Suppressor of

Statement

Reference

Scer\GAL4^ebd1.PB/arm^{S10.UAS.Tag:MYC} is a suppressor of indirect flight muscle cell phenotype of Scer\GAL4^ebd1.PB, pan^ΔN.UAS

(Benchabane et al., 2011)

Hsap\JRK^UAS.cBa, Scer\GAL4^ebd1.PB is a suppressor of indirect flight muscle cell phenotype of Scer\GAL4^ebd1.PB, pan^ΔN.UAS

(Benchabane et al., 2011)

Scer\GAL4^ebd1.PB/Hsap\JRK^UAS.cBa is a suppressor of indirect flight muscle cell phenotype of Df(3L)ED9698/ebd1²⁴⁰, ebd2¹³⁶

(Benchabane et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^ebd1.PB

Name Synonyms

earthbound 1 promoter construct of Benchabane

Secondary FlyBase IDs

References (3)

Report Sections