FlyBase Allele Report: Scer\GAL4[NP6293]

General Information

Symbol

Scer\GAL4^NP6293

Species

S. cerevisiae

Name

FlyBase ID

FBal0260977

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Bsg^NP6293

Carried in Construct

Also Known As

NP6293-Gal4, NP6293, PG-Gal4

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}Bsg^NP6293

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:8,088,298..8,088,397 [+]

(Carvalhas-Almeida et al., 2026, Cho et al., 2026, Avila et al., 2025, Chang et al., 2025, Chen et al., 2025, González-Gutiérrez et al., 2025, Lin et al., 2025, Zheng et al., 2025, Hu et al., 2024, Lin et al., 2024, Ma et al., 2024, Schmid et al., 2024, Ju et al., 2023, Li et al., 2023, Li et al., 2023, Shu et al., 2023, Wang et al., 2023, Chen et al., 2022, Weiss et al., 2022, Kowada et al., 2021, Lin et al., 2021, Park et al., 2021, Ryabova et al., 2021, Benmimoun et al., 2020, Chakravarti Dilley et al., 2020, Kim et al., 2020, Okamoto and Yamanaka, 2020, Wang et al., 2020, Connolly et al., 2019, Deng et al., 2019, Nakano et al., 2019, Wang et al., 2019, Yadav et al., 2019, Artiushin et al., 2018, Kanai et al., 2018, Kunduri et al., 2018, Stahl et al., 2018, Long and Giebultowicz, 2017, Skeath et al., 2017, Stratoulias and Heino, 2015, Stratoulias and Heino, 2015, Kerr et al., 2014, Spéder and Brand, 2014, Avet-Rochex et al., 2012, Belacortu et al., 2011, Ng et al., 2011, Strand and Micchelli, 2011, Awasaki et al., 2008)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval CNS perineurial glial cell

(Kanai et al., 2018, Spéder and Brand, 2014)

P-stage

CNS perineurial glial cell

(Nakano et al., 2019)

adult stage

adult brain perineurial glial cell

(Melom and Littleton, 2013, Awasaki et al., 2008)

adult midgut interstitial cell

(Strand and Micchelli, 2011)

adult midgut large flat cell

(Strand and Micchelli, 2011)

Additional Information

Statement

Reference

Drives expression in CNS perineurial sheath glial cells.

(FlyBase Curators, 2017)

Marker for

adult brain perineurial glial cell

(Melom and Littleton, 2013)

embryonic/larval CNS perineurial glial cell

(Kanai et al., 2018)

Reflects expression of

Bsg

(Melom and Littleton, 2013)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with sws^HMJ23229

(Ryabova et al., 2021)

abnormal neuroanatomy | P-stage, with egr^{TH201501125.S}

(Zheng et al., 2025)

abnormal neuroanatomy | P-stage, with Scer\GAL4^moody.PU, Scer\GAL4^nrv2.PU, egr^{TH201501125.S}

(Zheng et al., 2025)

abnormal neuroanatomy | third instar larval stage, with AdamTS-A^KK102087, Scer\GAL4^Gli-rL82

(Skeath et al., 2017)

abnormal neurophysiology | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with Mp^JF02929

(Wang et al., 2020)

abnormal neurophysiology | larval stage, with Sar1^KK108654

(Wang et al., 2020)

decreased occurrence of cell division | larval stage, with simba1^KK108629

(Lin et al., 2025)

decreased occurrence of cell division | larval stage, with simba2^KK111047

(Lin et al., 2025)

decreased occurrence of cell division | larval stage, with wg^GD5007

(Lin et al., 2025)

decreased occurrence of cell division | larval stage, with wg^KK108857

(Lin et al., 2025)

decreased occurrence of cell division | larval stage, with wls^GD2418

(Lin et al., 2025)

increased occurrence of cell division | larval stage, with simba1^{UAS.ORF.GW.Tag:HA}

(Lin et al., 2025)

increased occurrence of cell division | larval stage, with simba1^UAS.ORF-CC

(Lin et al., 2025)

increased occurrence of cell division | larval stage, with simba2^{UAS.ORF.GW.Tag:HA}

(Lin et al., 2025)

Phenotype Manifest In

adult brain, with sws^HMJ23229

(Ryabova et al., 2021)

dendrite | P-stage, with egr^{TH201501125.S}

(Zheng et al., 2025)

dendrite | P-stage, with Scer\GAL4^moody.PU, Scer\GAL4^nrv2.PU, egr^{TH201501125.S}

(Zheng et al., 2025)

embryonic/larval neuromuscular junction | larval stage, with Ada2b^JF01305

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with Mp^JF02929

(Wang et al., 2020)

embryonic/larval neuromuscular junction | larval stage, with Sar1^KK108654

(Wang et al., 2020)

larval brain | third instar larval stage, with AdamTS-A^KK102087, Scer\GAL4^Gli-rL82

(Skeath et al., 2017)

larval multidendritic class IV neuron | P-stage, with egr^{TH201501125.S}

(Zheng et al., 2025)

larval multidendritic class IV neuron | P-stage, with Scer\GAL4^moody.PU, Scer\GAL4^nrv2.PU, egr^{TH201501125.S}

(Zheng et al., 2025)

larval neuroblast, with simba1^KK108629

(Lin et al., 2025)

larval neuroblast, with simba1^{UAS.ORF.GW.Tag:HA}

(Lin et al., 2025)

larval neuroblast, with simba1^UAS.ORF-CC

(Lin et al., 2025)

larval neuroblast, with simba2^KK111047

(Lin et al., 2025)

larval neuroblast, with simba2^{UAS.ORF.GW.Tag:HA}

(Lin et al., 2025)

larval neuroblast, with wg^GD5007

(Lin et al., 2025)

larval neuroblast, with wg^KK108857

(Lin et al., 2025)

larval neuroblast, with wls^GD2418

(Lin et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^NP6293/wg^UAS.GFP is a suppressor | partially of decreased occurrence of cell division | larval stage phenotype of simba2^H3

(Lin et al., 2025)

Scer\GAL4^NP6293/wg^UAS.GFP is a suppressor | partially of decreased occurrence of cell division | larval stage phenotype of simba1^D5

(Lin et al., 2025)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^NP6293/wg^UAS.GFP is a suppressor | partially of larval neuroblast phenotype of simba2^H3

(Lin et al., 2025)

Scer\GAL4^NP6293/wg^UAS.GFP is a suppressor | partially of larval neuroblast phenotype of simba1^D5

(Lin et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

simba1^UAS.ORF-CC/Scer\GAL4^NP6293 partially rescues simba1^D5

(Lin et al., 2025)

simba2^{UAS.ORF.GW.Tag:HA}/Scer\GAL4^NP6293 partially rescues simba2^H3

(Lin et al., 2025)

Octβ2R^UAS.cDa/Scer\GAL4^NP6293 partially rescues Octβ2R^KOGal4

(Deng et al., 2019)

Fails to rescue

Scer\GAL4^NP6293/Cpes^UAS.cKa fails to rescue Cpes^KO

(Kunduri et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

105188

y^* w^*; P{GawB}Bsg^NP6293 / CyO, P{UAS-lacZ.UW14}UW14

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

NP6293^Gal4

(Strand and Micchelli, 2011)

Scer\GAL4^Bsg-NP6293

Scer\GAL4^NP6293

Name Synonyms

Secondary FlyBase IDs

References (51)

Report Sections

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