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General Information
Symbol
Scer\GAL4Ir76b.916
Species
S. cerevisiae
Name
FlyBase ID
FBal0264269
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
IR76b-Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 916bp fragment from immediately upstream of the Ir76b start codon is fused upstream of sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Scer\GAL4Ir76b.916 drives expression in ~24 S cells in metathoracic tarsal segment 5 and ~11 in metathoracic tarsal segment 3. The remaining metathoracic leg tarsal segments show sex specific differences, with tarsal segment 4 having ~14 neurons in females and ~22 in males, while tarsal segment 2 has ~10 in females and ~15 in males. Expression near completely overlaps with that of Scer\GAL4Ir76b.1.5, except that Scer\GAL4Ir76b.916 does not label L1 GRNs in the labellar taste bristles, some cells in the labellum nor axonal projections in the adult subesophageal zone that are labelled by the former.

Scer\GAL4Ir76b.916 is expressed in the neurons that innervate the antennal coeloconic sensillum ac1-a4 and in the antennal lobe glomeruli VM1, VM4, VC3 and VC5.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus with 617 nm (red) light) of Scer\GAL4Ir76b.916 cells in adult females significantly increases walking speed, but not angular speed, compared to baseline, whereas no increase is seen in controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4Ir76b.916
Name Synonyms
Secondary FlyBase IDs
    References (8)