FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gcmTag:FLAG
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General Information
Symbol
Dmel\gcmTag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0286127
Feature type
allele
Associated gene
Dmel\gcm
Associated Insertion(s)
Carried in Construct
M{gcm-FLAG.BAC}
Key Links
Transgenic product class
genomic_DNA
(Laneve et al., 2013)
wild_type
(Laneve et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Laneve et al., 2013)
wild_type
(Laneve et al., 2013)
Mutagen
in vitro construct
(Laneve et al., 2013)
Progenitor genotype
gcm+t36.5
(Laneve et al., 2013)
Carried in construct
M{gcm-FLAG.BAC}
Cytology
Description

Two copies of the Tag:FLAG tag has been inserted at the C-terminal end of the gcm coding region in the genomic fragment included in M{gcm.BAC}.

(Laneve et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
gcm
Encoded product / tool
gcm
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 5 -- 9
      head mesoderm
      (Laneve et al., 2013)
      embryonic stage 9
      embryonic longitudinal glial cell
      (Laneve et al., 2013)
      embryonic stage 10 -- 14
      embryonic hemocyte primordium
      (Laneve et al., 2013)
      embryonic stage 11 -- 13
      glial cell | subset of larval ventral nerve cord
      (Laneve et al., 2013)
      embryonic stage 11 -- 14
      larval ventral nerve cord
      (Laneve et al., 2013)
      embryonic stage 12
      tendon cell
      (Laneve et al., 2013)
      embryonic stage 13
      embryonic/larval peritracheal cell
      (Laneve et al., 2013)
      embryonic stage 13 -- 16
      glial cell | subset of larval brain
      (Laneve et al., 2013)
      neuron | subset of larval brain
      (Laneve et al., 2013)
      larval brain | lateral | restricted
      (Laneve et al., 2013)
      Additional Information
      Statement
      Reference

      In the embryo, gcmT:ZzzzFLAG transiently labels a subset of glial cells in the ventral nerve cord, hemocyte precursors, tendon cells, two symmetric clusters in the procephalic mesoderm, interface glial cells and peritracheal cells in the abdomen, thorax and head. Expression in the ventral nerve cord glial cells starts at stage 10, earlier than expression of repo, with colocalisation observed in stages 11 to 13. Expression is also observed in a few elav-positive cells in the embryonic brain at stage 16. After stage 16, expression of gcmT:ZzzzFLAG disappears.

      (Laneve et al., 2013)
       
      Marker for
      Reflects expression of
      gcm
      (Laneve et al., 2013)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      gcmT:Zzzz\FLAG
      gcmTag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)