FlyBase Allele Report: Dmel\rpr[lexAop.cSa]

General Information

Symbol

Dmel\rpr^lexAop.cSa

Species

D. melanogaster

Name

Escherichia coli lexAop construct a of Santabarbara-Ruiz

FlyBase ID

FBal0346745

Feature type

allele

Associated gene

Dmel\rpr

Associated Insertion(s)

Carried in Construct

P{lexAop-rpr.S}

Also Known As

LexO-rpr

Key Links

Transgenic product class

wild_type

(Santabárbara-Ruiz et al., 2015)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Santabárbara-Ruiz et al., 2015)

Mutagen

in vitro construct

(Santabárbara-Ruiz et al., 2015)

Progenitor genotype

Carried in construct

P{lexAop-rpr.S}

Cytology

Description

lexAop regulatory sequences drive expression of rpr (IP02529).

(Santabárbara-Ruiz et al., 2015)

Allele components

Component

Use(s)

Regulatory region(s)

lexAop

binary expression system - regulatory region

Encoded product / tool

rpr

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO

(Camilleri-Robles et al., 2024)

increased cell death | third instar larval stage, with Ecol\lexA^GAD.salm.EPv

(Sun et al., 2020)

visible | adult stage, with Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO

(Camilleri-Robles et al., 2024)

Phenotype Manifest In

wing, with Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO

(Camilleri-Robles et al., 2024)

wing pouch | third instar larval stage, with Ecol\lexA^GAD.salm.EPv

(Sun et al., 2020)

Detailed Description

Statement

Reference

Expression of rpr^lexAop.cSa under the control of Ecol\lexA^GAD.salm.EPv (in combination with Gal80[ts] to control the timing of expression) leads to executioner caspase activation and an increase in cell death in third instar larval wing pouch.

(Sun et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has visible | adult stage phenotype, suppressible | partially by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

NOT suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has decreased size | adult stage phenotype, non-suppressible by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

NOT Suppressor of

Statement

Reference

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of neoplasia | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ap-md544, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of increased cell number | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ap-md544, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of neoplasia | larval stage phenotype of BacA\p35^UAS.cHa, Scer\GAL4^hh.PU, rod^GD8768

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of neoplasia | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^UAS.C, rpr^lexAop.cSa, Ecol\lexA^GMR15B03, Scer\GAL4^He.PZ is a non-suppressor of neoplasia | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of neoplasia | larval stage phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of increased cell number | larval stage phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ecol\lexA^GAD.salm.EPv, lncRNA:CR40469^KO, rpr^lexAop.cSa has wing phenotype, suppressible | partially by Scer\GAL4^nub.PK/lncRNA:CR34335^UAS.cCa

(Camilleri-Robles et al., 2024)

NOT Suppressor of

Statement

Reference

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of wing disc phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of myoblast | increased number | larval stage phenotype of BacA\p35^UAS.cHa, Bub3^GD9924, Scer\GAL4^ap-md544

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of wing disc phenotype of BacA\p35^UAS.cHa, Scer\GAL4^hh.PU, rod^GD8768

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of wing disc phenotype of Ras85D^V12.UAS, Scer\GAL4^ap-md544, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of myoblast | increased number | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^ap-md544, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^lexAop.cSa/Ecol\lexA^GMR15B03 is a non-suppressor of wing disc phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, dlg1^GD4689

(Muzzopappa et al., 2017)

rpr^UAS.C, rpr^lexAop.cSa, Ecol\lexA^GMR15B03, Scer\GAL4^He.PZ is a non-suppressor of wing disc phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, dlg1^GD4689

(Muzzopappa et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

rpr^lexAop.cSa

Name Synonyms

Escherichia coli lexAop construct a of Santabarbara-Ruiz

Secondary FlyBase IDs

References (8)

Report Sections

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