Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\knk using the Feature Mapper tool.
knk protein is anchored to the apical cell surface of cells in the developing tracheae and epidermis. knk protein is observed to localize to the apical and apical-lateral surface of epithelial cells in the developing trachea from embryonic stage 15, and at the apical surface of epidermal cells from embryonic stage 16.
GBrowse - Visual display of RNA-Seq signalsView Dmel\knk in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Mutation in knk alters tracheal tube size in embryos without affecting other aspects of tracheal development including primary branch budding and outgrowth or branch fusion.
Zygotically active locus involved in the terminal developmental program in the embryo.