FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\por
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General Information
Symbol
Dmel\por
Species
D. melanogaster
Name
porcupine
Annotation Symbol
CG6205
Feature Type
protein_coding_gene
FlyBase ID
FBgn0004957
Gene Model Status
Current
Stock Availability
10 publicly available
Enzyme Name (EC)
Gene Summary
porcupine (por) encodes an O-acyltransferase that is an essential component of the Wingless/Wnt pathway by mediating lipidation of the product of wg. It targets the product of wg to secretory vesicles that deliver the ligand to specialized microdomains at the cell surface where it can be packaged for secretion. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

porc, 15175

Key Links
Genomic Location
Cytogenetic map
17A8-17A8
Sequence location
Recombination map
1-60
RefSeq locus
NC_004354 REGION:18377521..18379854
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (13 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
enables acyltransferase activity, transferring groups other than amino-acyl groups
inferred from mutant phenotype
(Zhai et al., 2004)
enables Wnt-protein binding
inferred from physical interaction with UniProtKB:P09615
(Tanaka et al., 2002)
inferred from physical interaction with UniProtKB:P28466
(Tanaka et al., 2002)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables palmitoleoyltransferase activity
inferred from biological aspect of ancestor with PANTHER:PTN001016659
(GO Reference Genome Project, 2011-)
inferred from sequence or structural similarity with UniProtKB:Q9JJJ7
(Gene Ontology Curators, 2002-)
enables Wnt-protein binding
inferred from biological aspect of ancestor with PANTHER:PTN001016659
(GO Reference Genome Project, 2011-)
Biological Process (7 terms)
Terms Based on Experimental Evidence (5 terms)
CV Term
Evidence
References
involved_in intracellular protein localization
inferred from mutant phenotype
(Zhai et al., 2004)
involved_in peptide hormone processing
inferred from mutant phenotype
(Kadowaki et al., 1996)
involved_in protein maturation
inferred from mutant phenotype
(Tanaka et al., 2002)
involved_in regulation of Wnt signaling pathway
inferred from mutant phenotype
(Kadowaki et al., 1996)
involved_in Wnt protein secretion
inferred from mutant phenotype
(Herr and Basler, 2012, Zhai et al., 2004, Kadowaki et al., 1996, van den Heuvel et al., 1993)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in lipid modification
inferred from biological aspect of ancestor with PANTHER:PTN000357522
(GO Reference Genome Project, 2011-)
involved_in Wnt protein secretion
inferred from biological aspect of ancestor with PANTHER:PTN001016659
(GO Reference Genome Project, 2011-)
involved_in Wnt signaling pathway
inferred from sequence or structural similarity with UniProtKB:Q9JJJ7
(Gene Ontology Curators, 2002-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in endoplasmic reticulum
inferred from direct assay
(Kadowaki et al., 1996)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in endoplasmic reticulum membrane
non-traceable author statement
(Kadowaki et al., 1996)
is_active_in endoplasmic reticulum
inferred from biological aspect of ancestor with PANTHER:PTN001016659
(GO Reference Genome Project, 2011-)
is_active_in membrane
inferred from biological aspect of ancestor with PANTHER:PTN000357522
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the membrane-bound acyltransferase family. Porcupine subfamily. (Q9VWV9)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
palmitoleoyltransferase activity
Summaries
Gene Snapshot
porcupine (por) encodes an O-acyltransferase that is an essential component of the Wingless/Wnt pathway by mediating lipidation of the product of wg. It targets the product of wg to secretory vesicles that deliver the ligand to specialized microdomains at the cell surface where it can be packaged for secretion. [Date last reviewed: 2019-03-14]
Pathway (FlyBase)
WNT PRODUCTION -
Factors required for the biogenesis and secretion of secretion of Wnt ligands.
Gene Group (FlyBase)
UNCLASSIFIED NON-AMINOACYL ACYLTRANSFERASES -
This group comprises non-aminoacyl acyltransferases that do not classify under other groups in FlyBase.
Protein Function (UniProtKB)
Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid ( C16:1 (9Z)), to Wnt proteins. Serine palmitoleoylation of Wnt proteins is required for efficient binding to frizzled receptors (By similarity). Also facilitates the glycosylation of Wnt family members, including wg and Wnt5. The cotranslational disulfide bond formation of wg competes with the N-glycosylation. Porc stimulates the post-translational N-glycosylation by anchoring wg at the ER membrane, probably through acylation (PubMed:11821428, PubMed:15166250, PubMed:22108505, PubMed:8985181).
(UniProt, Q9VWV9)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
porc: porcupine
Homo- and hemizygous lethal that affects segmentation pattern. porc/Y embryos from porc/porc germline clones show a segment polarity phenotype; porc/+ progeny from the germline clones become normal females.
Summary (Interactive Fly)

O-acyltransferase activity - mediates lipidation of Wingless, which targets Wingless to secretory vesicles that deliver the ligand to specialized microdomains at the cell surface where it can be packaged for secretion

Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\por for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VWV9)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.43

Gene model reviewed during 5.42

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
por-RA
FBtr0074577
NM_057542
2331
525
por-RB
FBtr0310487
NM_001272750
1848
525
por-RC
FBtr0333247
NM_001272751
2257
525
Additional Transcript Data and Comments
Reported size (kB)

2.4, 2.2 (northern blot)

(Kadowaki et al., 1996)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
por-PA
FBpp0074349
59.2
525
6.09
Q9VWV9
NP_476890
AAF48828
por-PB
FBpp0302628
59.2
525
6.09
Q9VWV9
NP_001259679
AGB95521
por-PC
FBpp0305446
59.2
525
6.09
Q9VWV9
NP_001259680
AGB95522
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

525 aa isoforms: por-PA, por-PB, por-PC
Additional Polypeptide Data and Comments
Reported size (kDa)

525 (aa); 59 (kD predicted)

(Kadowaki et al., 1996)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with wg and Wnt5.

(UniProt, Q9VWV9)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\por using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.72

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 1 -- 6

Comment: 0-3 hr AEL

(Kadowaki et al., 1996)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
(Kadowaki et al., 1996)
Additional Descriptive Data

The 2.4 kb por transcript is expressed throughout development.

(Kadowaki et al., 1996)

The 2.2 kb por transcript is maternal. It is detected in 0-3 hour embryos using in-situ hybridization.

(Kadowaki et al., 1996)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data

Epitope-tagged por protein localizes to the endoplasmic reticulum.

(Kadowaki et al., 1996)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in endoplasmic reticulum
inferred from direct assay
(Kadowaki et al., 1996)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\por in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 12 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of por
Transgenic constructs containing regulatory region of por
Aberrations (Deficiencies and Duplications) ( 5 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal | embryonic stage | rescuable maternal effect
lethal | germline clone | rescuable maternal effect
lethal | pupal stage | recessive
lethal | recessive
lethal | rescuable maternal effect
lethal - all die before end of larval stage | recessive
lethal - all die before end of pupal stage, with Scer\GAL4pnr-MD237
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
abnormal flight, with Scer\GAL4Mef2.PR
increased size | larval stage, with Scer\GAL4dve.PU
segment polarity phenotype
segment polarity phenotype | germline clone | rescuable maternal effect
some die during larval stage | recessive
some die during pupal stage, with Scer\GAL4pnr-MD237
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
abdominal 1 ventral denticle belt
abdominal 2 ventral denticle belt
abdominal 3 ventral denticle belt
abdominal 4 ventral denticle belt
abdominal 5 ventral denticle belt
abdominal 6 ventral denticle belt
abdominal 7 ventral denticle belt
abdominal tergite
antenna
bouton
chaeta | increased number, with Scer\GAL4pnr-MD237
embryo
embryonic/first instar larval cuticle | germline clone
embryonic/larval tracheal dorsal trunk | germline clone
embryonic head | germline clone
eye disc | larval stage, with Scer\GAL4dve.PU
interommatidial bristle
larval tracheal system | germline clone
leg
leg | distal
presumptive embryonic/larval central nervous system
sex comb
trichogen cell, with Scer\GAL4pnr-MD237
unguis | increased number
ventral denticle belt
ventral denticle belt | germline clone
wing
wing & macrochaeta
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (6)
Hsap\PORCN
13 of 14
Yes
Yes
Hsap\LPCAT3
1 of 14
No
No
1  
Hsap\MBOAT1
1 of 14
No
No
Hsap\MBOAT2
1 of 14
No
No
Hsap\MBOAT4
1 of 14
No
No
Hsap\MBOAT7
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (6)
Rnor\Porcn
13 of 14
Yes
Yes
Rnor\Lpcat3
1 of 14
No
No
Rnor\Mboat1
1 of 14
No
No
Rnor\Mboat2
1 of 14
No
No
Rnor\Mboat4
1 of 14
No
No
Rnor\Mboat7l1
1 of 14
No
No
Mus musculus (laboratory mouse) (6)
Mmus\Porcn
12 of 14
Yes
Yes
Mmus\Lpcat3
1 of 14
No
No
Mmus\Mboat1
1 of 14
No
No
Mmus\Mboat2
1 of 14
No
No
Mmus\Mboat4
1 of 14
No
No
Mmus\Mboat7
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (6)
Xtro\porcn
8 of 13
Yes
Yes
Xtro\LOC101732347
1 of 13
No
No
Xtro\mboat1
1 of 13
No
No
Xtro\mboat2
1 of 13
No
No
Xtro\mboat7
1 of 13
No
No
Xtro\slc2a11
1 of 13
No
No
Danio rerio (Zebrafish) (8)
Drer\porcn
13 of 14
Yes
Yes
Drer\porcnl
13 of 14
Yes
Yes
Drer\lpcat3
1 of 14
No
No
Drer\mboat1
1 of 14
No
No
Drer\mboat2a
1 of 14
No
No
Drer\mboat2b
1 of 14
No
No
Drer\mboat4
1 of 14
No
No
Drer\mboat7
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (5)
Cele\mom-1
12 of 14
Yes
Yes
Cele\mboa-3
1 of 14
No
No
Cele\mboa-4
1 of 14
No
No
Cele\mboa-6
1 of 14
No
No
Cele\mboa-7
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (4)
Agam\PORCN_ANOGA
11 of 12
Yes
Yes
Agam\AgaP_AGAP007567
1 of 12
No
No
Agam\AgaP_AGAP009259
1 of 12
No
No
Agam\AgaP_AGAP012258
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (2)
Atha\LPLAT1
2 of 13
Yes
No
Atha\LPLAT2
2 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\ALE1
3 of 13
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPBC16A3.10
2 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:por. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (3)
frj
3 of 13
nes
3 of 13
oys
3 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    PORCN; porcupine O-acyltransferase
    model of  focal dermal hypoplasia
    IEA
    (FlyBase, 2019-)
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    PORCN; porcupine O-acyltransferase
    13 of 14
    300651
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    Summary of Genetic Interactions
    Interaction Browsers
    View in FlyBase Interactions Browser   View in MIST tool (external link)
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    nkd
    enhanceable
    por
    (Zeng et al., 2000)
    Nsf2
    enhanceable
    por
    (Stewart et al., 2001)
    Wnt5
    suppressible
    por
    (Fradkin et al., 2004)
    External Data
    Subunit Structure (UniProtKB)
    Interacts with wg and Wnt5.
    (UniProt, Q9VWV9 )
    Linkouts
    BioGRID - A database of protein and genetic interactions.
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    FlyBase
    External Links
    External Data
    Linkouts
    KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
    SignaLink - A signaling pathway resource with multi-layered regulatory networks.
    Class of Gene
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    X
    Recombination map
    1-60
    Cytogenetic map
    17A8-17A8
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    17A8-17A8
    Limits computationally determined from genome sequence between P{EP}EP1378 and P{EP}CG32549EP1317
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    17A5-17A7
    (Kadowaki, 1996.11.4)
    Experimentally Determined Recombination Data
    Location

    1-60

    (FlyBase, 2016)

    1-59.2

    (Comeron et al., 2012)

    1-59

    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (10)
    Genomic Clones (10)
     

    Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

    cDNA Clones (89)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    Other clones
    RNAi and Array Information
    Linkouts
    DRSC - Results frm RNAi screens
    Antibody Information
    Laboratory Generated Antibodies
     
    Commercially Available Antibodies
     
    Cell Line Information
    Publicly Available Cell Lines
     
      Other Stable Cell Lines
       
        Other Comments

        por is required for lipidation of the wg protein and for the subsequent targeting of the modified wg protein to specialised lipid raft detergent-insoluble microdomains at the cell surface.

        (Zhai et al., 2004)

        The por gene product encodes an evolutionarily conserved putative multi-transmembrane protein that primarily localises to the endoplasmic reticulum (ER) and is involved in wg processing. por acts nonautonomously in wg patterning.

        (Kadowaki et al., 1996)

        The por gene product is required for wg-dependent bristle inhibition.

        (Cadigan and Nusse, 1995)

        por is required for direct wg autoregulation and is epistatic to sgg in the regulation of wg. por is required for autoregulation by exogenous wg.

        (Manoukian et al., 1995)

        The por gene product behaves non-autonomously in mitotic cell clones.

        (Noordermeer et al., 1994)

        dsh and por act upstream of sgg, and arm acts downstream of sgg in the wg signalling pathway. por acts upstream of sgg.

        (Siegfried et al., 1994)

        wg and en expression patterns are studied in all known segment polarity mutants to investigate the requirement of other segment polarity genes in mediating the maintenance of wg and en.

        (van den Heuvel et al., 1993)

        Embryos mutant for por show a retention of the wg product in the wg expressing cells, suggesting that por provides an accessory function for wg protein secretion or transport.

        (van den Heuvel et al., 1993)

        Germline clonal analysis demonstrates that mutations of por do not alter oogenesis.

        (Ferrus et al., 1990)

        The role of segment polarity genes in arm protein accumulation has been investigated. In por mutant embryos arm stripes were difficult to detect and when observed they were much narrower and weaker than wild type. wg regulates accumulation of arm by posttranscriptional control, por and dsh are also required for this effect.

        (Riggleman et al., 1990)
        Relationship to Other Genes
        Source for database merge of
        Additional comments

        FlyBase curator comment: the insertion in the "f08025" Exelixis line (PBac{WH}CG6179f08025) was originally assigned to the por gene in FBrf0179797, resulting in the "porf08025" (FBal0158796) allele. However, FBrf0184340 shows that the insertion is actually within CG6179.

        (Bloomington Drosophila Stock Center, 2004.11.6)
        Nomenclature History
        Source for database identify of

        Source for identity of: por CG6205

        (Li, 1999.11)
        Nomenclature comments
        Etymology
        Synonyms and Secondary IDs (11)
        Reported As
        Symbol Synonym
        15175
        (de la Pompa, 1994, Ferrus et al., 1990)
        CG6205
        (Hosono et al., 2015, Ni et al., 2010.12.1, Keleman et al., 2009.8.5)
        Por
        (Alvarez-Rodrigo et al., 2023)
        Porc
        (Jenny and Basler, 2014, Nusse, 2003, Bhat, 1999)
        dmPorc
        (Chamoun et al., 2001)
        l(1)17Ac
        poc
        (Martinez Arias, 1993)
        por
        (Graves et al., 2020, Transgenic RNAi Project members, 2017-, Moulton and Letsou, 2016, Sarov et al., 2016, Yamamoto et al., 2013-, Herr and Basler, 2012, Toku et al., 2011, Popodi et al., 2010-, Venken et al., 2010, Steinhauer et al., 2009, Chen et al., 2008, Ching et al., 2008, Linder and Deschenes, 2004)
        porc
        (Puli et al., 2024, Mehta et al., 2021, Zhang et al., 2016, Kerr et al., 2014, Kopyl et al., 2010, Kopyl et al., 2010, Wouda et al., 2008, Fradkin et al., 2004, Zhai et al., 2004, Yu, 2003, Galis et al., 2002, Tanaka et al., 2002, Stewart et al., 2001, Strigini and Cohen, 2000, Tanaka et al., 2000, Zeng et al., 2000, Ruvkun and Hobert, 1998, Cadigan and Nusse, 1997, Cadigan and Nusse, 1996, Ingham, 1996, Kadowaki et al., 1996, Manoukian et al., 1995, Noordermeer et al., 1995, DiNardo et al., 1994, Klingensmith and Nusse, 1994, Noordermeer et al., 1994, Siegfried and Perrimon, 1994, Siegfried et al., 1994, van den Heuvel et al., 1993, Peifer and Bejsovec, 1992, Woods and Bryant, 1992, Ingham, 1991, Ingham, 1991, Wilkins and Gubb, 1991)
        Name Synonyms
        Porcupine
        (Ahmed-de-Prado and Baonza, 2018, Shilo, 2016, Jenny and Basler, 2014, Steinhauer et al., 2009, Ching and Nusse, 2007, Coudreuse and Korswagen, 2007)
        porcupine
        (Graves et al., 2020, Tian et al., 2019, Kerr et al., 2014, Chen et al., 2008, Wouda et al., 2008, Clevers, 2006, Wendler et al., 2006, Linder and Deschenes, 2004, Kadowaki, 1996.11.4)
        Secondary FlyBase IDs
        • FBgn0003126
        Datasets (0)
        Study focus (0)
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        Study result (0)
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        External Crossreferences and Linkouts ( 44 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
        UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
        EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
        FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
        FlyMine - An integrated database for Drosophila genomics
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        MARRVEL_MODEL - MARRVEL (model organism gene)
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
        Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
        KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        SignaLink - A signaling pathway resource with multi-layered regulatory networks.
        References (130)