FlyBase Gene Report: Dmel\CG33523

General Information

Symbol

Dmel\CG33523

Species

D. melanogaster

Name

Annotation Symbol

CG33523

Feature Type

protein_coding_gene

FlyBase ID

FBgn0053523

Gene Model Status

Current

Stock Availability

10 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

dVAP-B, MSP protein

Key Links

Genomic Location

Cytogenetic map

64F5-65A1

Sequence location

3L:5,923,862..5,930,120 [+]

Recombination map

3-16

RefSeq locus

NT_037436 REGION:5923862..5930120

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (2 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in endomembrane system

inferred from biological aspect of ancestor with PANTHER:PTN005301323

(GO Reference Genome Project, 2011-)

is_active_in endoplasmic reticulum-endosome membrane contact site

inferred from biological aspect of ancestor with PANTHER:PTN005301323

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CG33523 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry M9PBR6)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model includes transcripts encoding non-overlapping portions of the full CDS.

Stop-codon suppression (UAA) postulated; FBrf0216885.

Gene model reviewed during 5.44

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.45

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CG33523-RA

FBtr0091478

NM_001014566

1508

234

CG33523-RB

FBtr0091476

NM_001014568

1360

206

CG33523-RC

FBtr0091477

NM_001014567

1656

240

CG33523-RD

FBtr0091475

NM_001014569

2574

498

CG33523-RE

FBtr0306383

NM_001259713

2672

285

CG33523-RF

FBtr0330119

NM_001274528

2574

654

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

CG33523-PA

FBpp0090957

25.8

234

9.29

FBpp0090955

22.7

206

9.30

FBpp0090956

26.4

240

9.06

FBpp0090954

56.4

498

7.74

FBpp0297475

32.9

285

5.74

FBpp0303152

73.1

654

6.08

M9PBR6

NP_001261457

AGB94152

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CG33523 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

4.53

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 5 of adulthood | male -- day 7 of adulthood | male

spermatozoon

(Wasbrough et al., 2010, Dorus et al., 2006)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\CG33523 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\CG33523

View exonic expression by tissue for Dmel\CG33523

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38668/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0053523

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0053523

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0053523

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33523

Flygut - An atlas of the Drosophila adult midgut

FBgn0053523

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 17 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of CG33523

Transgenic constructs containing regulatory region of CG33523

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3L)Exel7210

(Ryder, 2004.4.26)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

CG33523^GD2326

lethal, with Scer\GAL4^insc-Mz1407

CG33523^GD2326

lethal - all die during embryonic stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

CG33523^GD2326

lethal - all die during P-stage, with Scer\GAL4^Mef2.PR

CG33523^GD2326

partially lethal - majority die, with Scer\GAL4^pnr-MD237

CG33523^GD2326

viable

viable, with Scer\GAL4^Mef2.PR

CG33523^GD10886

viable, with Scer\GAL4^pnr-MD237

CG33523^GD10886

viable, with Scer\GAL4^tin.CΔ4

CG33523^GD2326

Sterility

Allele

fertile

Other Phenotypes

Allele

abnormal neuroanatomy | larval stage, with Scer\GAL4^elav-C155

CG33523^EP3539

abnormal neuroanatomy | larval stage, with Scer\GAL4^insc-Mz1407

CG33523^GD2326

some die during pupal stage, with Scer\GAL4^pnr-MD237

CG33523^GD2326

visible, with Scer\GAL4^pnr-MD237

CG33523^GD2326

Phenotype manifest in

Allele

anterior fascicle & synapse, with Scer\GAL4^elav-C155

CG33523^EP3539

eye, with Scer\GAL4^GMR.PF

CG33523^GD2326

ganglion mother cell | larval stage, with Scer\GAL4^insc-Mz1407

CG33523^GD2326

larval intersegmental nerve, with Scer\GAL4^elav-C155

CG33523^EP3539

larval neuroblast | larval stage, with Scer\GAL4^insc-Mz1407

CG33523^GD2326

mesonotum, with Scer\GAL4^pnr-MD237

CG33523^GD2326

trichogen cell, with Scer\GAL4^pnr-MD237

CG33523^GD2326

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (17)

Hsap\MOSPD2

13 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (16)

Rnor\Mospd2

13 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (16)

Mmus\Mospd2

13 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (9)

Xtro\mospd2

8 of 13

Yes

Xtro\b3galt2l

1 of 13

Xtro\clvs1

1 of 13

Xtro\necab2

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (15)

Drer\mospd2

13 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (75)

Cele\hpo-28

13 of 14

Yes

Cele\ZC196.2

3 of 14

Cele\C10H11.7

2 of 14

Yes

Cele\C15H11.1

2 of 14

Yes

Cele\F28H7.8

2 of 14

Cele\F38H4.6

2 of 14

Yes

Cele\F42G2.5

2 of 14

Cele\F52F12.8

2 of 14

Yes

Cele\F54H5.3

2 of 14

Cele\F57A10.2

2 of 14

Yes

Cele\H41C03.1

2 of 14

Cele\K05F1.9

2 of 14

Yes

Cele\R05D3.5

2 of 14

Yes

Cele\T05D4.5

2 of 14

Yes

Cele\T22B3.3

2 of 14

Yes

Cele\vpr-1

2 of 14

Cele\ZC262.1

2 of 14

Yes

Cele\ZK354.7

2 of 14

Yes

Cele\ZK688.12

2 of 14

Yes

Cele\C15H11.13

1 of 14

Yes

Cele\C34C12.6

1 of 14

Cele\C34D10.1

1 of 14

Yes

Cele\C35E7.9

1 of 14

Yes

Cele\C36H8.1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Cele\F53B6.4

1 of 14

Yes

Cele\K08E3.2

1 of 14

Yes

Cele\msp-3

1 of 14

Yes

Cele\msp-10

1 of 14

Yes

Cele\msp-19

1 of 14

Yes

Cele\msp-31

1 of 14

Yes

Cele\msp-32

1 of 14

Yes

Cele\msp-33

1 of 14

Yes

Cele\msp-36

1 of 14

Yes

Cele\msp-38

1 of 14

Yes

Cele\msp-40

1 of 14

Yes

Cele\msp-45

1 of 14

Yes

Cele\msp-49

1 of 14

Yes

Cele\msp-50

1 of 14

Yes

Cele\msp-51

1 of 14

Yes

Cele\msp-53

1 of 14

Yes

Cele\msp-55

1 of 14

Yes

Cele\msp-56

1 of 14

Yes

Cele\msp-57

1 of 14

Yes

Cele\msp-59

1 of 14

Yes

Cele\msp-63

1 of 14

Yes

Cele\msp-64

1 of 14

Yes

Cele\msp-65

1 of 14

Yes

Cele\msp-76

1 of 14

Yes

Cele\msp-77

1 of 14

Yes

Cele\msp-78

1 of 14

Yes

Cele\msp-79

1 of 14

Yes

Cele\msp-81

1 of 14

Yes

Cele\msp-113

1 of 14

Yes

Cele\msp-142

1 of 14

Yes

Cele\msp-152

1 of 14

Yes

Cele\R03A10.5

1 of 14

Cele\spe-47

1 of 14

Yes

Cele\ssp-19

1 of 14

Yes

Cele\ssp-32

1 of 14

Yes

Cele\ssp-36

1 of 14

Yes

Cele\T03F7.7

1 of 14

Cele\T23G5.2

1 of 14

Cele\W03D8.5

1 of 14

Yes

Cele\Y53C10A.15

1 of 14

Yes

Cele\Y53F4B.19

1 of 14

Yes

Cele\Y59E9AR.1

1 of 14

Yes

Cele\Y59E9AR.7

1 of 14

Yes

Cele\Y59H11AM.1

1 of 14

Yes

Cele\Y116A8A.2

1 of 14

Yes

Cele\Y116A8A.7

1 of 14

Yes

Cele\ZK973.4

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (45)

Agam\AgaP_AGAP005556

11 of 12

Yes

2 of 12

2 of 12

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (42)

Atha\AT5G63060

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (8)

Scer\CSR1

3 of 13

Yes

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (7)

Spom\SPAC3H8.02

4 of 12

Yes

3 of 12

3 of 12

2 of 12

2 of 12

2 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:CG33523. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (30)

9 of 13

5 of 13

4 of 13

2 of 13

fan

2 of 13

mcw

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

MOSPD2; motile sperm domain containing 2

13 of 14

301086

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

CG33523 - AIF

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - Ask1

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - Bcs1

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - CG10494

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - CG1513

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - CG33191

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - CG9205

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - GAPcenA

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - Sk2

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - Vap33

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - az2

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - cert

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - cliff

experimental knowledge based

(Guruharsha et al., 2011)

CG33523 - h-cup

two hybrid

(Hu et al., 2017.6.13)

CG33523 - rdgB

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

64128

DroID - A comprehensive database of gene and protein interactions.

FBgn0053523

MIST (protein-protein) - An integrated Molecular Interaction Database

38668

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

gene_with_stop_codon_read_through

(Jungreis, 2011.11.18)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-16

Cytogenetic map

64F5-65A1

Sequence location

3L:5,923,862..5,930,120 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

64F5-65A1

Limits computationally determined from genome sequence between P{PZ}vn¹⁰⁵⁶⁷ and P{PZ}loj⁰⁴⁰²⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-16

(FlyBase, 2016)

3-14.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

25838

y¹ v¹; P{TRiP.JF01856}attP2

18128

w¹¹¹⁸; PBac{RB}CG33523^e03176

27948

y¹ w^*; P{EP}CG33523^G4280

52199

y¹ w^*; Mi{MIC}CG33523^MI09717

15331

y¹ w^67c23; P{EPgy2}CG33523^EY01207

Kyoto

104706

w^*; P{GawB}CG33523^NP4600 / TM3, Ser¹

10977R-3

32410R-1

v110519

v37237

w¹¹¹⁸; P{GD2326}v37237

Genomic Clones (24)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (105)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0053523

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0053523

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Area matching Drosophila ESTS AA802887 and AA820871. These ESTs have sequence similarity to C. elegans protein B0336.11.

(Davies, 2001.3.15)

Relationship to Other Genes

Source for database merge of

Source for merge of: CG10977 BcDNA:GH09028

(FlyBase, 1996-)

Source for merge of: CG10977 CG32410

(FlyBase Genome Annotators, 2005)

Additional comments

Annotations CG10977 and CG32410 merged as CG33523 in release 4.1 of the genome annotation.

(FlyBase Genome Annotators, 2005)

Annotation CG10727 split into CG32407 and CG32410 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

FlyBase curator comment: BLAST analysis and a subsequent paper by the same group (FBrf0202930) confirms that 'VAP-33B' refers to 'CG33523'.

(Pennetta et al., 2002)

Source for merge of CG10977 BcDNA:GH09028 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: Vap-33B CG33523

(Pennetta et al., 2002)

Source for identity of: CG33523 Vap-33B

(Pennetta, 2016.5.9)

Nomenclature comments

Symbol of this gene reverted from 'Vap-33B' back to 'CG33523' as it is now apparent that it does not encode a canonical VAP protein.

(Pennetta, 2016.5.9)

Etymology

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

BcDNA:GH09028

CG10727

CG10977

(Giot et al., 2003, Oliver, 2001.8.16)

CG32410

CG33523

(Pang et al., 2021, Hu et al., 2017.6.13, Çiçek et al., 2016, Cockcroft and Raghu, 2016, Aradska et al., 2015, Hosono et al., 2015, Kwon et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Jungreis, 2011.11.18, Levis et al., 2011.12.16, Arancio et al., 2010, Gan et al., 2010, Wasbrough et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Tan et al., 2009, Chai et al., 2008, Jordan et al., 2007, Dorus et al., 2006)

Vap-33B

dVAP-B

(Yadav et al., 2018, Cockcroft and Raghu, 2016)

Name Synonyms

MSP protein

(Kraut et al., 2001, Kraut et al., 2001)

VAMP-associated protein of 33kDa ortholog B

Secondary FlyBase IDs

FBgn0035650
FBgn0035651
FBgn0052410
FBgn0064970
FBtr0077033
FBpp0076741
FBtr0077034
FBpp0076742
FBtr0077035
FBpp0076743
FBtr0077036
FBpp0076744

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

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External Crossreferences and Linkouts ( 87 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38668

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

M9PBR6

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

M9PBR6

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38668/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0053523

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0053523

FlyMine - An integrated database for Drosophila genomics

FBgn0053523

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG33523

MARRVEL_MODEL - MARRVEL (model organism gene)

38668

Linkouts

BioGRID - A database of protein and genetic interactions.

64128

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0053523

DroID - A comprehensive database of gene and protein interactions.

FBgn0053523

DRSC - Results frm RNAi screens

FBgn0053523

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0053523

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0053523

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG33523

Flygut - An atlas of the Drosophila adult midgut

FBgn0053523

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0053523

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC002960

MIST (protein-protein) - An integrated Molecular Interaction Database

38668

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (60)

The following external sites may use different assemblies or annotations than FlyBase.

4.53

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