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Citation
Goulding, S.E., zur Lage, P., Jarman, A.P. (2000). amos, a proneural gene for Drosophila olfactory sense organs that is regulated by lozenge.  Neuron 25(1): 69--78.
FlyBase ID
FBrf0126762
Publication Type
Research paper
Abstract

In a variety of organisms, early neurogenesis requires the function of basic-helix-loop-helix (bHLH) transcription factors. For the Drosophila PNS, such transcription factors are encoded by the proneural genes (atonal and the achaete-scute complex, AS-C). We have identified a proneural gene, amos, that has strong similarity with atonal in its bHLH domain. We present evidence that amos is required for olfactory sensilla and is regulated by the prepattern gene lozenge. Between them, amos, atonal, and the AS-C can potentially account for the origin of the entire PNS.

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Note

Specificity and promiscuity among proneural proteins.
Bray, 2000, Neuron 25(1): 1--2 [FBrf0126759]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Neuron
    Title
    Neuron
    Publication Year
    1988-
    ISBN/ISSN
    0896-6273
    Data From Reference
    Aberrations (3)
    Alleles (14)
    Genes (14)
    Insertions (3)
    Experimental Tools (1)
    Transgenic Constructs (4)