Chammout, H., Adkins, D.L., Al-Olimat, A.K., Alsaad, Z., Altopp, B.M., Amer, T., Apampa, F.O., Avery, G.R., Bazzi, I.I., Beck, E.D., Beier, E.L., Belisle, B.S., Benton, L., Bolyard, M.M., Brain, O.E., Buckner, E.T., Chowdhury, S.R., Cifranic, J.R., Cleary, L., Clum, T.R., Cruz, A.M., DeGray, M.V., Echeverry, I.L., El Dana, H., Elkadri, S.K., Estep, P.L., Falke, L.R., Foor, H.J., Gullapalli, A.S., Hakim, S.S., Hazime, H.B., Heininger, L.E., Hoeft, E.G., James, L.M., Jeon, Y., Johnson, M.R., Jordan, L.P., Khan, Z., Kochensparger, S.K., Koria, F.J., Krasnow, R.M., Lilly, V., Lim, E., MacCormack, I.T., Malesh, A., Mariano, M.G., Mentzer, A.C., Messner, K.H., Myers, K.C., Newman, E.R., Richters, A.M., Romero, L., Rotem, A., Saho, R.J., Sawaki, K., Selders, A.N., Shockney, E., Sobh, F.A., Speiser, I.F., Sproul, B.M., Sroufe, V.J., Tollkuci, A., Trevino, C.C., Vapenik, M.A., Wagner, E.M., Bieser, K.L., Siders, J.L., Thackeray, J.R., Kagey, J.D. (2024). G.3.2 is a novel allele of the gene connector enhancer of ksr (cnk) in Drosophila melanogaster.  MicroPubl Biol 2024(): .

FBrf0260640

Research paper

Genetic screens in Drosophila melanogaster have long been used to identify genes found in a variety of developmental, cellular, and behavioral processes. Here we describe the characterization and mapping of a mutation identified in a conditional screen for genetic regulators of cell growth and cell division. Within a Flp/FRT system, mutant G.3.2 results in a reduction of mutant tissue and a rough eye phenotype. We find that G.3.2 maps to the gene cnk , providing further support that cnk is a critical gene in Drosophila eye development. This mutant was characterized, mapped and sequenced by undergraduate students within the Fly-CURE consortium.

PMC11467748 (PMC) (EuropePMC)