FB2025_01 , released February 20, 2025
Complex: MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS
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General Information
Name
MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS
Species
D. melanogaster
Symbol
MRPL
FlyBase ID
FBgg0000181
Date last reviewed
2024-10-18
Number of members
53
Description
Description
Mitochondrial ribosomes are found in the mitochondrial matrix and translate genes involved in oxidative phosphorylation encoded by the mitochondrial genome. Ribosomes are formed by two ribonucleoprotein subunits, large and small. The principle function of the large subunit is to bind tRNA during the synthesis of polypeptides. (Adapted from FBrf0205398).
Notes on Group

The MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS gene group includes mitochondrial rRNA.

Based on data from the human orthologs (PMID:25278503), mRpS18A has been assigned to both the MITOCHONDRIAL SMALL RIBOSOMAL COMPONENTS and MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS gene groups, and mRpS30 has been moved from MITOCHONDRIAL SMALL RIBOSOMAL COMPONENTS to the MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS gene group (FBrf0260754).

Source Material
The MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS Gene Group has been compiled using the following publication(s): Attrill and Marygold, 2024.10.18, Wredenberg et al., 2013, and Marygold et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
structural constituent of ribosome
Biological Process
translation
Cellular Component
mitochondrial large ribosomal subunit
mitochondrial matrix
Related Gene Groups
Parent group(s)
MITOCHONDRIAL RIBOSOMAL COMPONENTS
Members (53)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG6094
(Attrill and Marygold, 2024.10.18)
CG14817
EG:63B12.11
(Attrill and Marygold, 2024.10.18)
CRIF
CR6-interacting factor
(Attrill and Marygold, 2024.10.18)
mRpL1
mitochondrial ribosomal protein L1
(Marygold et al., 2007)
mRpL2
mitochondrial ribosomal protein L2
(Marygold et al., 2007)
mRpL3
mitochondrial ribosomal protein L3
(Marygold et al., 2007)
mRpL4
mitochondrial ribosomal protein L4
l(2)35Fe, l(2)k14608, BG:DS02740.17
(Marygold et al., 2007)
mRpL9
mitochondrial ribosomal protein L9
(Marygold et al., 2007)
mRpL10
mitochondrial ribosomal protein L10
(Marygold et al., 2007)
mRpL11
mitochondrial ribosomal protein L11
rpl-11
(Marygold et al., 2007)
mRpL12
mitochondrial ribosomal protein L12
l(3)10534, mRpL7-L12, Mrp17
(Marygold et al., 2007)
mRpL13
mitochondrial ribosomal protein L13
(Marygold et al., 2007)
mRpL14
mitochondrial ribosomal protein L14
EG:BACH48C10.6
(Marygold et al., 2007)
mRpL15
mitochondrial ribosomal protein L15
l(3)77CDc
(Marygold et al., 2007)
mRpL16
mitochondrial ribosomal protein L16
EG:63B12.2, D-15, anon-2Bd
(Marygold et al., 2007)
mRpL17
mitochondrial ribosomal protein L17
(Marygold et al., 2007)
mRpL18
mitochondrial ribosomal protein L18
(Marygold et al., 2007)
mRpL19
mitochondrial ribosomal protein L19
(Marygold et al., 2007)
mRpL20
mitochondrial ribosomal protein L20
(Marygold et al., 2007)
mRpL21
mitochondrial ribosomal protein L21
(Marygold et al., 2007)
mRpL22
mitochondrial ribosomal protein L22
L22
(Marygold et al., 2007)
mRpL23
mitochondrial ribosomal protein L23
(Marygold et al., 2007)
mRpL24
mitochondrial ribosomal protein L24
(Marygold et al., 2007)
mRpL27
mitochondrial ribosomal protein L27
(Marygold et al., 2007)
mRpL28
mitochondrial ribosomal protein L28
(Marygold et al., 2007)
mRpL30
mitochondrial ribosomal protein L30
(Marygold et al., 2007)
mRpL32
mitochondrial ribosomal protein L32
(Marygold et al., 2007)
mRpL33
mitochondrial ribosomal protein L33
(Marygold et al., 2007)
mRpL34
mitochondrial ribosomal protein L34
(Marygold et al., 2007)
mRpL35
mitochondrial ribosomal protein L35
(Marygold et al., 2007)
mRpL36
mitochondrial ribosomal protein L36
(Marygold et al., 2007)
mRpL37
mitochondrial ribosomal protein L37
(Marygold et al., 2007)
mRpL38
mitochondrial ribosomal protein L38
(Marygold et al., 2007)
mRpL39
mitochondrial ribosomal protein L39
mRpL5
(Marygold et al., 2007)
mRpL40
mitochondrial ribosomal protein L40
(Marygold et al., 2007)
mRpL41
mitochondrial ribosomal protein L41
(Marygold et al., 2007)
mRpL42
mitochondrial ribosomal protein L42
(Marygold et al., 2007)
mRpL43
mitochondrial ribosomal protein L43
(Marygold et al., 2007)
mRpL44
mitochondrial ribosomal protein L44
(Marygold et al., 2007)
mRpL45
mitochondrial ribosomal protein L45
(Marygold et al., 2007)
mRpL46
mitochondrial ribosomal protein L46
(Marygold et al., 2007)
mRpL47
mitochondrial ribosomal protein L47
Rlc1
(Marygold et al., 2007)
mRpL48
mitochondrial ribosomal protein L48
(Marygold et al., 2007)
mRpL49
mitochondrial ribosomal protein L49
(Marygold et al., 2007)
mRpL50
mitochondrial ribosomal protein L50
(Marygold et al., 2007)
mRpL51
mitochondrial ribosomal protein L51
(Marygold et al., 2007)
mRpL52
mitochondrial ribosomal protein L52
(Marygold et al., 2007)
mRpL53
mitochondrial ribosomal protein L53
(Marygold et al., 2007)
mRpL54
mitochondrial ribosomal protein L54
(Marygold et al., 2007)
mRpL55
mitochondrial ribosomal protein L55
tom thumb, tmb
(Marygold et al., 2007)
mRpS18A
mitochondrial ribosomal protein S18A
mRpS18c
(Attrill and Marygold, 2024.10.18)
mRpS30
mitochondrial ribosomal protein S30
(Attrill and Marygold, 2024.10.18)
mt:lrRNA
mitochondrial large ribosomal RNA
mtlrRNA, 16S, lrRNA, 16S rRNA, mitochondrial large rRNA
(Wredenberg et al., 2013)
External Data
Equivalent Group(s)
Other resource(s)

[Ribosomal Protein Gene Database: D.MEL MITOCHONDRIAL RIBOSOMAL PROTEINS](http://ribosome.med.miyazaki-u.ac.jp/rpg.cgi?mode=orglist&org=Drosophila%20melanogaster&type=m)

Synonyms and Secondary IDs
Synonym(s)
MRPL
Large mitochondrial ribosomal subunit
Large mitoribosome
large mitochondrial ribosome
MITOCHONDRIAL LARGE RIBOSOMAL COMPONENTS
MITOCHONDRIAL LARGE RIBOSOMAL PROTEINS
Secondary FlyBase ID(s)
References (4)