FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(1)RK4
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General Information
Symbol
Df(1)RK4
Species
D. melanogaster
Name
FlyBase ID
FBab0000676
Feature type
chromosomal_deletion
Computed Breakpoints include

12F5-12F6;13A9-13B1

Features within 12F5--13B1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
In(1)P363
(Drysdale et al., 1991)
In(1)N282.2
(Drysdale et al., 1991)
Mutagen
recombination
(Drysdale et al., 1991)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Cook et al., 1997, Pauli et al., 1995, Livingstone, 1985)
Breakpoints

12F5-12F6;13A9-13B1

(Cook et al., 1997, Pauli et al., 1995, Livingstone, 1985)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

NetB << bk1 << rut << eag << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0043474)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Adcy1
(Mitchell et al., 1996, Livingstone, 1985)
eag
(Lear et al., 2005, Drysdale et al., 1991)
hiw
(Wan et al., 2000)
Partially deleted / disrupted
Molecular Data
Completely deleted
drd
(Dzitoyeva et al., 2003)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Transmission rate of Dp(1;f)J21A through females to progeny is 28%, Df(1)RK4 weakly decreases transmission.

    (Cook et al., 1997)
    NOT in combination with other aberrations

    Some mutant embryos show minor cuticular abnormalities, with the denticle belt typically being interrupted or missing from abdominal segment A4. A larger number of mutant embryos have more severe phenotypes, such as a complete lack of denticle belts. Mouth hook formation is not affected. Extensive embryonic lethality is seen in mutant animals.

    (Dzitoyeva et al., 2003)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Midgut development of mutant embryos is wild type.

    (Bilder and Scott, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Hemizygous embryos were examined with polarised light microscopy and antibody staining: muscle pattern abnormal due principally to variably expressed defect in insertion site positioning.

    (Drysdale et al., 1993)
    Stocks (1)
    Notes on Origin
    Discoverer

    W.R. Engels.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(1)RK4
    (Blumenthal, 2008, Crest et al., 2007, Lear et al., 2005, Dzitoyeva et al., 2003)
    In(1)N282.2LP363R
    RK4
    (Wan et al., 2000)
    Name Synonyms
    Secondary FlyBase IDs
      References (24)