FlyBase Aberration Report: Dmel\Df(3R)red-P52

General Information

Symbol

Df(3R)red-P52

Species

D. melanogaster

Name

Deficiency (3R) red Malpighian tubules

FlyBase ID

FBab0002874

Feature type

chromosomal_deletion

Also Known As

Df(3R)red^p52, Df(3R)redP52

Computed Breakpoints include

88A4;88B1-88B2

Features within 88A4--88B2

Sequence coordinates

3R:14,309,646..14,312,195 [+] (Df(3R)red-P52:bk2)

(Harrison et al., 1992)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Landis et al., 1997)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Ghabrial et al., 1998, Landis et al., 1997, Hamilton et al., 1993, Kelley, 1993, Dalton et al., 1989)

Breakpoints

88A4;[]

(Dalton et al., 1989)

88A4;88B1-88B2

(Kelley, 1993)

88A12-88B1;88B4-88B5

(Ghabrial et al., 1998, Hamilton et al., 1993)

88A2-88A4;88B1-88B2

(Landis et al., 1997)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

ems << bk1 << mei-P19 << RpII15 << bk2 << spn-B

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Breen and Harte, 1991, Parkhurst and Ish-Horowicz, 1991, Parkhurst et al., 1988)

Comments on Cytology

300kb deletion that removes the entire trx gene.

(Breen et al., 1995)

Limits of break 1 from polytene analysis (FBrf0049810) Left limit of break 2 from inclusion of 140up (FBrf0054607) Right limit of break 2 from polytene analysis (FBrf0058539)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

l(3)88Ac

(Jarman and Collett, 1998)

l(3)88Ad

(Jarman and Collett, 1998)

l(3)88Bb

(Mortin et al., 1992, Breen and Harte, 1991)

l(3)88Bc

(Mortin et al., 1992, Breen and Harte, 1991)

l(3)88Bd

(Mortin et al., 1992, Breen and Harte, 1991)

Orc2

(Jarman and Collett, 1998, Landis et al., 1997, Mortin et al., 1992)

Polr2B

(Jarman and Collett, 1998, Mortin et al., 1992, Breen and Harte, 1991)

Polr2I

(Mortin et al., 1992, Breen and Harte, 1991)

rdx

(Seong et al., 2010, Jarman and Collett, 1998, Mortin et al., 1992)

red

(Landis et al., 1997, Mortin et al., 1992, Breen and Harte, 1991)

su(Hw)

(Jarman and Collett, 1998, Landis et al., 1997, Mortin et al., 1992, Breen and Harte, 1991, Lewis, 1981)

Timmdc1

(Mortin et al., 1992, Breen and Harte, 1991)

trx

(Landis et al., 1997, Breen et al., 1995, BDGP Project Members, 1994-1999, Mortin et al., 1992, Breen and Harte, 1991, Castelli-Gair and Garcia-Bellido, 1990, Duncan, 1986, Capdevila and Garcia-Bellido, 1981)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

cv-c

(Breen and Harte, 1991)

Dip-B

(Jarman and Collett, 1998)

ems

(Jarman and Collett, 1998, Dalton et al., 1989)

spn-B

(Ghabrial et al., 1998, Tearle and Nusslein-Volhard, 1987)

tefu

(Queiroz-Machado et al., 2001)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Aberration fails to complement Df(3R)red3l, Df(3R)293γ5, Df(3R)293γ7, Df(3R)M49, Df(3R)M36, Df(3R)su(Hw)7 and Df(3R)red-P1 and complements Df(3R)l26c.

(Jarman and Collett, 1998)

NOT in combination with other aberrations

Heterozygotes show abnormal temperature-preference behaviour; their avoidance index against low temperatures is reduced compared to wild type.

(Bang et al., 2011)

Heterozygosity for Df(3R)red-P52 results in 3.4% X chromosome nondisjunction and 1.7% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Df(3R)red-P52 is hemizygous embryonic lethal. 10.5% of heterozygous adults show at least one homeotic transformation phenotype.

(Breen, 1999)

Homozygous lethal.

(Landis et al., 1997)

Visible phenotype is not altered in the presence of Usp47^Evar1.

(Henchoz et al., 1996)

Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the abx regulatory region have an increased frequency of the trx bithorax-variegated phenotype (partial transformation of T3 to T2, mostly in the anterior compartment). Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the pbx regulatory region have an increased frequency of the trx bithorax-variegated phenotype, although a large fraction of the transformations are to posterior T3 structures. Flies heterozygous for both Df(3R)red-P52 and Ubx mutations in the bx and bxd regulatory regions show no increase in the trx bithorax-variegated phenotype, except Ubx^bx-F31 and Ubx^bx-34eprv which both overlap the region affected by abx deletions.

(Castelli-Gair and Garcia-Bellido, 1990)

The A1 transformation phenotype of ftz^Ual alleles is suppressed in Df(3R)red-P52 / ftz^Ual allele heterozygotes. The haltere to wing transformation of ftz^Rpl is slightly enhanced in ftz^Rpl / Df(3R)red-P52 heterozygotes.

(Duncan, 1986)

Heterozygotes sometimes have transformations typical of bithorax or postbithorax mutants.

(Capdevila and Garcia-Bellido, 1981)

Df(3R)red/+ progeny of Df(1)C128/+ females show a high frequency of homeotic transformations (Gans et al., 1980).

Stocks (6)

Bloomington

3484

Df(3R)red-P52/TM1

1900

Df(3R)red-P52, Ubx^abx-1/TM1

3485

Df(3R)red-P52, Sb^sbd-2 Ubx^bx-3 Ubx^pbx-1/TM1

Kyoto

107060

Df(3R)red-P52/TM1

106565

Df(3R)red-P52, Ubx^abx-1/TM1

107061

Df(3R)red-P52, Sb^sbd-2 Ubx^bx-3 Ubx^pbx-1/TM1

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Second breakpoint not reported.

(Dalton et al., 1989)

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df(3R)red-P52

(Bang et al., 2011, Seong et al., 2010)

Df(3R)red^P52

(Maixner et al., 1998, Henchoz et al., 1996, Breen et al., 1995, Chinwalla et al., 1995, Kelley, 1993, Harrison et al., 1992, Mortin et al., 1992, Breen and Harte, 1991, Castelli-Gair and Garcia-Bellido, 1990, Harrison et al., 1989, Parkhurst et al., 1988, Duncan, 1986, Capdevila and Garcia-Bellido, 1981)

Df(3R)red^p52

(Harris et al., 2003, Loupart et al., 2000, Dalton et al., 1989)

Df(3R)redP52

(Queiroz-Machado et al., 2001, Breen, 1999, Ghabrial et al., 1998, Hamilton et al., 1993)

DfredP52

(Landis et al., 1997)

Name Synonyms

Deficiency (3R) red Malpighian tubules

Secondary FlyBase IDs

References (33)

Report Sections

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