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General Information
Symbol
Dmel\brm1
Species
D. melanogaster
Name
FlyBase ID
FBal0001295
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

brm1/brm16 heterozygous females have greatly reduced fertility.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

brm1 is a suppressor of lethal phenotype of Ras85DV12.sev, sevS11.Tag:MYC

brm1/brm[+] is a suppressor of visible | homeotic phenotype of AntpNs, Pc2

Other
Phenotype Manifest In
Suppressor of
Statement
Reference

brm1/brm[+] is a suppressor of eye phenotype of Scer\GAL4ey.PH, asf1UAS.cMa

brm1/brm[+] is a suppressor of antenna phenotype of AntpNs, Pc2

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

HcfHR1 shows leg defects when in double heterozygous combination with brm1 (20% penetrance).

γTub23CPl-2 results in a held-out wing phenotype in double heterozygous combination with brm1 (35% penetrance).

The lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev is suppressed by brm1.

Suppresses the antenna to leg transformation phenotype of Pc2, AntpNs/+. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Not rescued by
Comments

Homozygous and hemizygous lethality is rescued by brm+t14.4. Four copies of brmΔ549-610.T:Ivir\HA1 fail to rescue the lethality of brm1 homozygotes.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)