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General Information
Symbol
Dmel\osa00090
Species
D. melanogaster
Name
FlyBase ID
FBal0009367
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)00090, osa13
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion 780bp upstream of the first Met residue, in the first intron. The P{PZ} element is inserted in the opposite orientation to the direction of osa transcription.

P{PZ} insertion in the first intron.

P{PZ} insertion in the first intron, downstream of a non-coding exon.

Insertion components
P{PZ}osa00090
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Each Malpighian tubule develops two tip cells in osa00090/osadust55 and osa00090/osadust31 embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

osa00090/osa[+] is an enhancer of visible | heat sensitive phenotype of peb1

osa00090 is an enhancer of visible | dominant phenotype of KrIf-1

osa00090/osa[+] is an enhancer of visible | dominant phenotype of KrIf-1

Suppressor of
Phenotype Manifest In
Enhancer of
Statement
Reference

osa00090/osa[+] is an enhancer of eye | heat sensitive phenotype of peb1

osa00090 is an enhancer of eye phenotype of KrIf-1

osa00090 is an enhancer of ommatidium phenotype of KrIf-1

osa00090/osa[+] is an enhancer of eye phenotype of KrIf-1

NOT Enhancer of
Statement
Reference

osa00090/osa[+] is a non-enhancer of leg phenotype of e(y)34

osa00090/osa[+] is a non-enhancer of wing vein | ectopic phenotype of net1

Suppressor of
NOT Suppressor of
Statement
Reference

osa00090/osa[+] is a non-suppressor of wing vein | ectopic phenotype of net1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The formation of ectopic wing veins observed in adult flies expressing Marcal1Scer\UAS.cBa under the control of Scer\GAL4tub.PU is ameliorated by combination with a single copy of osa00090.

Flies heterozygous for osa00090 show suppression of the Scer\GAL4GMR.PS, DrefScer\UAS.cSa severe rough eye phenotype; eyes are modestly rough and fused ommatidia are not apparent.

35% of Df(2R)ED3921/+; osa00090/+ flies show a held out wing phenotype, while neither single mutant shows this phenotype. The penetrance is increased to 100% in Df(2R)ED3921; osa00090/+ flies. The wing vein phenotype of Df(2R)ED3921 single mutants is enhanced by osa00090, resulting in loss of L5 up to the posterior crossvein.

Suppresses the CycEJP rough eye phenotype.

Xenogenetic Interactions
Statement
Reference

The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1Scer\UAS.cBa under the control of Scer\GAL4Bx-MS1096 is ameliorated by combination with a single copy of osa00090.

Introduction of osa00090/+ significantly increases total MN5 dendritic length and dendritic number above that in the Hsap\MECP2Scer\UAS.FL, Scer\GAL4futsch-C380, Scer\GAL80Cha.3.3P background.

Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (9)
References (20)