Open Close
General Information
Symbol
Dmel\brnpr-7
Species
D. melanogaster
Name
FlyBase ID
FBal0013161
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
npr17
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes arrest development at the end of the larval period, do not pupariate and die after several days as wandering third instar larvae.

Lethality acts in the late third instar.

Heterozygotes with br1 display small maxillary palps that are virtually devoid of mechanosensory bristles. Rostral membrane is lost so the proboscis is barely visible.

Failure of salivary gland degeneration. Reduction in dorso-ventral class of indirect flight muscles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Partially rescued by

brnpr-7 is partially rescued by brZ2.hs

Comments

Lethality is not rescued by brBRcore.Q1.Z1.hs, brBRcore.TNT.Q1.Z1.hs, brZ2.hs, brBRcore.NS.Z3.hs or brBRcore.Z4.hs when expressed using heat shocks of either 33oC or 37oC. brnpr-7 third instar larvae expressing brZ2.hs show further development than control brnpr-7 larvae, forming normal looking puparia with everted spiracles, a tanned cuticle and imaginal discs that have initiated morphogenesis.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (12)