Open Close
General Information
Symbol
Dmel\ttkosn
Species
D. melanogaster
Name
oversensitive
FlyBase ID
FBal0024415
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}ttkosn
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

IIa precursor is transformed into a IIb precursor.

Homozygotes have more sensory neurons than normal.

Overproduction of sensory neurons. Defects in the embryonic PNS, number of es and cho neurons is approximately doubled due to transformation of the outer support cell and cap cell respectively. Mosaic analysis demonstrates loss of ttk function in the adult leads to the appearance of supernumerary neurons at the expense of hair and socket cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

ttk[+]/ttkosn is an enhancer of visible phenotype of phyl2/phyl4

Suppressor of
Statement
Reference

ttk[+]/ttkosn is a suppressor of visible | recessive phenotype of msi1

ttk[+]/ttkosn is a suppressor of visible phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of visible phenotype of sina3/sina2

NOT Suppressor of
Statement
Reference
Other
Statement
Reference
Phenotype Manifest In
NOT Enhanced by
Statement
Reference

ttkosn has sensory neuron | supernumerary phenotype, non-enhanceable by phyl1/phyl2

NOT suppressed by
Statement
Reference
Enhancer of
Statement
Reference

ttk[+]/ttkosn is an enhancer of adult abdominal segment 3 & chaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is an enhancer of adult abdominal segment 3 & tormogen cell | supernumerary phenotype of phyl2/phyl4

ttk[+]/ttkosn is an enhancer of adult abdominal segment 3 & trichogen cell | supernumerary phenotype of phyl2/phyl4

ttk[+]/ttkosn is an enhancer of adult abdominal segment 4 & chaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is an enhancer of adult abdominal segment 4 & tormogen cell | supernumerary phenotype of phyl2/phyl4

ttk[+]/ttkosn is an enhancer of adult abdominal segment 4 & trichogen cell | supernumerary phenotype of phyl2/phyl4

Suppressor of
Statement
Reference

ttk[+]/ttkosn is a suppressor of trichogen cell | supernumerary phenotype of msi1

ttk[+]/ttkosn is a suppressor of adult abdominal segment 3 & microchaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of adult abdominal segment 3 & microchaeta phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 3 & tormogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 3 & trichogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 4 & chaeta phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 4 & microchaeta phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 4 & tormogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 4 & trichogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & chaeta phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & tormogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & trichogen cell | supernumerary phenotype of sina3/sina2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 4 & microchaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & chaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & microchaeta phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & tormogen cell | supernumerary phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of mesothoracic tergum & trichogen cell | supernumerary phenotype of phyl2/phyl4

ttk[+]/ttkosn is a suppressor of eo neuron | embryonic stage phenotype of phyl1/phyl2

ttk[+]/ttkosn is a suppressor of adult abdominal segment 3 & chaeta phenotype of sina3/sina2

ttkosn is a suppressor | partially of phenotype of msi1

ttkosn is a suppressor of ommatidium phenotype of msi1, sina3/sina2

ttkosn is a suppressor of rhabdomere phenotype of msi1, sina3/sina2

ttkosn is a suppressor of cone cell phenotype of msi1, sina3/sina2

ttkosn is a suppressor | partially of phenotype of sina3

ttkosn is a suppressor | partially of phenotype of sina2

Other
Additional Comments
Genetic Interactions
Statement
Reference

The partial lethality due to runScer\UAS.cLa; Scer\GAL4nos.PG (3% viable) is not suppressed by maternal heterozygosity for ttkosn.

30% of the ommatidia of sina2 msi1 ttkosn/sina3 msi1 show the normal number and arrangement of photoreceptor cells. The cone cell defects of sina2 msi1/sina3 msi1 are also suppressed by ttkosn.

numb1;ttkosn double mutant overproduces neurons, indistinguishable from ttkosn mutant.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
oversensitive
Secondary FlyBase IDs
    References (9)