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General Information
Symbol
Dmel\ScmET50
Species
D. melanogaster
Name
FlyBase ID
FBal0030201
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G9636274A

Amino acid change:

G275E | Scm-PA; G275E | Scm-PB

Reported amino acid change:
Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: G275E.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

ScmET50 is an enhancer of visible | dominant | homeotic phenotype of Pc3

ScmET50 is an enhancer of partially lethal | dominant phenotype of Pc3

NOT Enhancer of
Statement
Reference
NOT Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Enhancer of
Statement
Reference

ScmET50 is an enhancer of phenotype of Pc15

Suppressor of
Statement
Reference

ScmET50/Scm[+] is a suppressor of eye phenotype of Hsap\MECP2UAS.FL, Scer\GAL4GMR.PU

ScmET50/Scm[+] is a suppressor of eye phenotype of Hsap\MECP2Δ166.UAS, Scer\GAL4GMR.PU

ScmET50 is a suppressor of phenotype of z1

Additional Comments
Genetic Interactions
Statement
Reference

ScmET50 suppresses the pairing-dependent silencing of wenh.iab-7PRE.410 seen in flies homozygous for P{iab-7PRE-wenh.410}1 or P{iab-7PRE-wenh.410}2. ScmET50 suppresses the pairing-dependent silencing of wenh.iab-7PRE.260 seen in flies homozygous for P{iab-7PRE-wenh.260}1 or P{iab-7PRE-wenh.260}2.

The addition of heterozygous ScmET50 can suppress the Pairing sensitive silencing effect seen in wMcp.10, wMcp.13, wMcp.scs'.12:15, wMcp.scs'.11 and wMcp.scs'.14. The addition of heterozygous ScmET50 has no effect on the Pairing sensitive silencing effect seen in wMcp.11. the addition of heterozygous ScmET50 strongly suppresses the Pairing sensitive silencing effect seen in wMcp.scs'.11 (P{Mcp-w#11}16/+, P{Mcp-w#11}102/+) double heterozygous insertions. The addition of heterozygous ScmET50 strongly suppresses the Pairing sensitive silencing effect seen in wMcp.scs'.14/ wMcp.13 (P{Mcp-w#14}AP-2stummelbein/+, P{Mcp-w#13}116/+) double heterozygous insertions.

Dominantly enhances the homeotic phenotypes of Pc3/+ adults. Partially lethal in double heterozygous combination with Pc3, Pc2 or SceD1. ph-p409 males that are also heterozygous for ScmET50 show partial lethality.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
ScmET50
Name Synonyms
Secondary FlyBase IDs
    References (8)