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General Information
Symbol
Dmel\sno71e3
Species
D. melanogaster
Name
FlyBase ID
FBal0032749
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

sno71e3/Y males show slight notching of the wing and wing vein thickening. The flies also have a rough eye phenotype.

At 23oC flies exhibit a modest loss of wing margin tissue and thickening of wing veins. Flies heat pulsed during pupariation do not exhibit a hypertrophic bristle phenotype on the notum and photoreceptor organisation behind the morphogenetic furrow is regular.

At 23oC adults have rough eyes: bristles misplaced and sometimes duplicated. 30% of ommatidia have lost one or more R cells, and 30% contained an extra R cell. At 19oC eyes are more normal. At 23oC wings are notched and veins are thickened, and this phenotype is more severe at 27oC and absent at 19oC. Fourth and fifth tarsal segments are fused with 80% penetrance at 23oC, and wild type at 19oC. Females are poorly fertile at 23oC and completely sterile at 27oC. At 25oC the number of ovarioles per female is reduced by 25%, and defects in cystoblast survival and polarity are evident. Temperature sensitive period is in the prepupal and pupal stages. Phenotypes of sno71e3 are similar to those of Nl1N-ts1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference

sno71e3 has wing margin phenotype, enhanceable by ebik16213

sno71e3 has wing margin phenotype, enhanceable by vg[+]/vg1

sno71e3 has wing margin phenotype, enhanceable by wgl-12/wg[+]

sno71e3 has wing margin phenotype, enhanceable by ct53d/ct[+]

sno71e3 has phenotype, enhanceable by Nnd-1

sno71e3 has phenotype, enhanceable by Nnd-2

Suppressed by
Statement
Reference

sno71e3 has wing margin phenotype, suppressible by H[+]/HE31

sno71e3 has phenotype, suppressible by H99

NOT suppressed by
Statement
Reference

sno71e3 has phenotype, non-suppressible by mam10

sno71e3 has phenotype, non-suppressible by bib1

sno71e3 has phenotype, non-suppressible by neur11

Enhancer of
Statement
Reference

sno71e3 is an enhancer of phenotype of Nnd-1

sno71e3 is an enhancer of phenotype of Nnd-2

Suppressor of
Statement
Reference

sno71e3 is a suppressor of phenotype of NAx-E2

sno71e3 is a suppressor of phenotype of NAx-9

sno71e3 is a suppressor of wing vein phenotype of Dl3

sno71e3 is a suppressor of phenotype of H99

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The notching of the wing and wing vein thickening seen in sno71e3/Y males is enhanced by CG6194P0997/CG6194P0997. The sno71e3/Y rough eye phenotype is also enhanced.

Loss of a single copy of wg (wgl-12), ct (ct53d) or vg (vg1) in sno71e3 flies causes extensive loss of wing margin tissue. Single copy loss of H (HE31) is able to suppress the wing margin defects of sno71e3 flies. Loss of a single copy of Su(H) (Su(H)2) causes pupal lethality at 23oC and at 20oC some pupae eclose and exhibit severe wing margin defects.

A duplication of N rescues many of the defects of sno mutants. There is a synergistic interaction with 'nd' alleles of N, and a suppressive interaction with alleles of the 'Ax' class of N. H99 and sno71e3 show a mutually suppressive interaction. The confluens phenotype of Dl3 is suppressed by sno71e3. Flies hemizygous for sno71e3 and heterozygous for groE73 suffer lethality with a few escapers that show an eye roughening phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)