mesothoracic tergum & macrochaeta | somatic clone | cell non-autonomous
Pka-C1E95, sggM11 smo3 triple mutant clones in the wing disc exhibit some outgrowths from the notum but no significant wing pattern duplications. Wing discs with Pka-C1E95, smo3 clones have large expansions affecting the anterior compartment of the wing disc.
The non-autonomous extra macrochaetae phenotype of homozygous clones is suppressed if the clones are also homozygous for dppH61. Unlike Pka-C1E95 clones, sgg32 Pka-C1E95 double mutant clones in the medial prescutum produce macrochaetae autonomously, and unlike sgg32 clones, the double mutant clones have a symmetrical bristle pattern. In the posterior scutum, sgg32 Pka-C1E95 double mutant clones have a scutellar phenotype very similar to that of Pka-C1E95 clones. In the anterior scutum, sgg32 Pka-C1E95 double mutant clones no longer show the non-autonomous induction of macrochaetae or formation of pits characteristic of Pka-C1E95 clones. Formation of macrochaetae within the double mutant clones is increased relative to sgg32 clones.
Clones double mutant for dppH61 Pka-C1E95 do not cause supernumerary structures in the leg and wing. Clones positioned at the compartment boundary exhibit long range effects causing a marked reduction in wing size and loss of vein pattern in anterior and posterior compartments. Short range effects include inducing immediate neighbours to form ectopic veins and margin bristles, the clones fail to differentiate wing veins in a cell autonomous fashion. dppd12 Pka-C1E95 also fail to form veins in the anterior compartment. wgl-17 Pka-C1E95 clones cause local outgrowths of leg tissue and on rare occasions form of supernumerary legs.