FlyBase Allele Report: Dmel\Rho1[k07903]

General Information

Symbol

Dmel\Rho1^k07903

Species

D. melanogaster

Name

FlyBase ID

FBal0061656

Feature type

allele

Associated gene

Dmel\Rho1

Associated Insertion(s)

P{lacW}Rho1^k07903

Carried in Construct

Also Known As

RhoA^P2

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Strutt et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}Rho1^k07903

Cytology

Description

Insertion of a P{lacW} element, within an intron.

(Strutt et al., 1997)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Strutt et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Rho1^k07903 is a non-enhancer of abnormal cell polarity phenotype of fz²⁰/fz¹⁹

(Strutt and Strutt, 2003)

Rho1^k07903 is a non-enhancer of visible phenotype of Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-enhancer of visible phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-enhancer of visible phenotype of Rala^S25N.UAS, Scer\GAL4^sca-537.4

(Sawamoto et al., 1999)

Suppressor of

Statement

Reference

Rho1^k07903 is a suppressor of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, dsh^UAS.cNa

(Strutt et al., 1997)

Rho1^k07903 is a suppressor of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, fz^UAS.cAa

(Strutt et al., 1997)

NOT Suppressor of

Statement

Reference

Rho1^k07903 is a non-suppressor of visible phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-suppressor of visible phenotype of Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-suppressor of visible phenotype of Rala^S25N.UAS, Scer\GAL4^sca-537.4

(Sawamoto et al., 1999)

Phenotype Manifest In

Enhancer of

Statement

Reference

Rho1^k07903 is an enhancer of eye phenotype of Rac1^N17.UAS, Scer\GAL4^hs.2sev

(Fanto et al., 2000)

Rho1^k07903 is an enhancer of ommatidium phenotype of Rac1^N17.UAS, Scer\GAL4^hs.2sev

(Fanto et al., 2000)

NOT Enhancer of

Statement

Reference

Rho1^k07903 is a non-enhancer of ommatidium phenotype of fz²⁰/fz¹⁹

(Strutt and Strutt, 2003)

Rho1^k07903 is a non-enhancer of eye phenotype of Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-enhancer of eye phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Suppressor of

Statement

Reference

Rho1^k07903 is a suppressor of ommatidium phenotype of Rac1^V12.hs.sev

(Fanto et al., 2000)

Rho1^k07903 is a suppressor of eye phenotype of Rac1^V12.hs.sev

(Fanto et al., 2000)

Rho1^k07903 is a suppressor of phenotype of dsh^hs.sev.B

(Boutros et al., 1998)

Rho1^k07903 is a suppressor of ommatidium phenotype of Scer\GAL4^hs.2sev, dsh^UAS.cNa

(Strutt et al., 1997)

Rho1^k07903 is a suppressor of ommatidium phenotype of Scer\GAL4^hs.2sev, fz^UAS.cAa

(Strutt et al., 1997)

NOT Suppressor of

Statement

Reference

Rho1^k07903 is a non-suppressor of eye phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Rho1^k07903 is a non-suppressor of eye phenotype of Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

Fails to complement: lola⁰⁰⁶⁴².

(BDGP Project Members, 1994-1999)

Excision of the P{lacW} element reverts the lethal phenotype.

(Strutt et al., 1997)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Rho1^k07903

RhoA^P2

(Uchida et al., 2002, Fanto, 2000, Fanto et al., 2000, Sawamoto et al., 1999, Strutt et al., 1997)

RhoA^k07903

(Strutt and Strutt, 2003)

l(2)k07903

(Strutt et al., 1997)

rhoA^P2

(Molnar and de Celis, 2006, Boutros et al., 1998)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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