FlyBase Allele Report: Dmel\tai[k05809]

General Information

Symbol

Dmel\tai^k05809

Species

D. melanogaster

Name

FlyBase ID

FBal0064465

Feature type

allele

Associated gene

Dmel\tai

Associated Insertion(s)

P{lacW}tai^k05809

Carried in Construct

Also Known As

l(2)k05809

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}tai^k05809

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:9,176,383..9,176,383 [+]

(Bai et al., 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage (with Df(2L)ED678)

(Zhang et al., 2015)

decreased body size | adult stage (with Df(2L)ED678)

(Zhang et al., 2015)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

border follicle cell (with tai^61G1)

(McDonald et al., 2003)

wing (with Df(2L)ED678)

(Zhang et al., 2015)

Detailed Description

Statement

Reference

tai^k05809/Df(2L)ED678 mutant adults are small and show a significant reduction in wing size, relative to controls.

(Zhang et al., 2015)

Border follicle cells show migration defects in stage 10 tai^61G1/tai^k05809 egg chambers; in 74% of egg chambers they have migrated 76-100% the normal distance, in 15% they have migrated 51-75% the normal distance, in 6% they have migrated 26-50% the normal distance and in 5% they have migrated 0-25% the normal distance.

(McDonald et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

tai[+]/tai^k05809 is a suppressor of abnormal size phenotype of Scer\GAL4^en.PU, crb^{intra.UAS.Tag:MYC}

(Zhang et al., 2015)

Other

Statement

Reference

Df(2R)M60E/+, tai^k05809 has partially lethal - majority die phenotype

(McDonald et al., 2003)

Tp(3;Y)ry506-85C/+, tai^k05809 has partially lethal - majority die phenotype

(McDonald et al., 2003)

Df(2L)J39/+, tai^k05809 has lethal phenotype

(McDonald et al., 2003)

Phenotype Manifest In

Enhancer of

Statement

Reference

tai^k05809/tai^61G1 is an enhancer of border follicle cell phenotype of Pvf1^UAS.cMa, Scer\GAL4^slbo.2.6

(McDonald et al., 2003)

Suppressor of

Statement

Reference

tai[+]/tai^k05809 is a suppressor of wing phenotype of Scer\GAL4^en.PU, crb^{intra.UAS.Tag:MYC}

(Zhang et al., 2015)

Other

Statement

Reference

Df(3R)3450/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3R)H-B79/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3R)by10/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3R)crb-F89-4/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3R)crb87-4/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(1)N19/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(1)v-N48/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

+/Df(2L)BSC7, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(2L)Dwee-δ5/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(2L)J2/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3L)AC1/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Df(3L)GN24/+, tai^k05809 has border follicle cell phenotype

(McDonald et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

The presence of tai^k05809/+ suppresses the enlarged wings of adult females expressing crb^{intra.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en.PU.

(Zhang et al., 2015)

The border cells migration defects caused by expression of Pvf1^Scer\UAS.cMa under the control of Scer\GAL4^slbo.2.6 are enhanced by tai^61G1/tai^k05809; all the double mutant egg chambers show border cell migration defects.

(McDonald et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

12172

y¹ w^67c23; P{lacW}tai^k05809/CyO

Kyoto

102418

y¹ w^67c23 ; P{lacW}tai^k05809 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: tai⁰¹³⁵¹.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

l(2)k05809

(Bai et al., 2000, Spradling et al., 1999)

l(2)k05809^k05809

(BDGP Project Members, 1994-1999)

tai⁰⁵⁸⁰⁹

(Zhang et al., 2015)

tai^k05809

(Zhang et al., 2015, Ito et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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