FlyBase Allele Report: Dmel\mei-W68[k05603]

(Iida and Lilly, 2004, Shulman and McKim, 2000.6.20, Spradling et al., 1999, McKim and Hayashi-Hagihara, 1998, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

viable

(Shulman and McKim, 2000.6.20)

Phenotype Manifest In

Detailed Description

Statement

Reference

The majority of mei-W68¹/mei-W68^k05603 eggs (94%) show a wild-type number of dorsal appendages.

(Klattenhoff et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

mei-W68¹/mei-W68^k05603 is a suppressor | maternal effect of dorsal appendage | maternal effect phenotype of CycG^HR7

(Nagel et al., 2012)

mei-W68[+]/mei-W68^k05603 is a suppressor | partially of nurse cell phenotype of mio²/mio¹

(Iida and Lilly, 2004)

mei-W68[+]/mei-W68^k05603 is a suppressor | partially of oocyte phenotype of mio²/mio¹

(Iida and Lilly, 2004)

mei-W68[+]/mei-W68^k05603 is a suppressor of nurse cell phenotype of mio²

(Iida and Lilly, 2004)

mei-W68[+]/mei-W68^k05603 is a suppressor of oocyte phenotype of mio²

(Iida and Lilly, 2004)

NOT Suppressor of

Statement

Reference

mei-W68^k05603/mei-W68^k05603 is a non-suppressor | maternal effect of embryo | maternal effect phenotype of PolD3^R2/PolD3^NR42

(Tritto et al., 2015)

mei-W68¹/mei-W68^k05603 is a non-suppressor of dorsal appendage phenotype of armi^72.1/armi¹

(Klattenhoff et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

The types and frequency of defects seen in embryos derived from Pol32^NR42/Pol32^R2 females is not altered if the females are also homozygous for mei-W68^k05603.

(Tritto et al., 2015)

The ventralised eggshell phenotype seen in eggs derived from homozygous CycG^HR7 females is suppressed in more than 90% of eggs if the females are also carrying mei-W68¹/mei-W68^k05603.

(Nagel et al., 2012)

The fused dorsal appendage phenotype of armi^72.1/armi¹ eggs is not suppressed in mei-W68¹/mei-W68^k05603; armi^72.1/armi¹ eggs.

(Klattenhoff et al., 2007)

Transformation of oocytes to nurse cells in mio²/mio² or mio²/mio¹ females is partially suppressed by mei-W68^k05603/+.

(Iida and Lilly, 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

10574

y¹ w^67c23; P{lacW}mei-W68^k05603 par-1^k05603/CyO

Kyoto

108858

y¹ w^67c23; P{lacW}mei-W68^k05603/CyO

111182

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}mei-W68^k05603 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: l(2)k06617^k06617. Complements: px^k08316. Complements: l(2)k09801^k09801. Complements: l(2)k13211^k13211. Complements: l(2)k17026^k17026.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

l(2)k05603

(Shulman and McKim, 2000.6.20, Palmer et al., 1999, Spradling et al., 1999)

l(2)k05603^k05603

mei-W68^K05603

(Klattenhoff et al., 2009)

mei-W68^k05603

(Tritto et al., 2015, Nagel et al., 2012, Klattenhoff et al., 2007)

mei-W68^k

(Jansen et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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